Mus musculus
TRP63
AI462811, Ket, P51/P63, P63, P73l, Tp63, Trp53rp1
transformation related protein 63
GO Process (66)
GO Function (13)
GO Component (12)
Gene Ontology Biological Process
- DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [IBA]
- anatomical structure formation involved in morphogenesis [IMP]
- apoptotic process [TAS]
- cell aging [IMP]
- cell differentiation [IMP]
- cellular response to DNA damage stimulus [ISO]
- cellular response to UV [IBA]
- chromatin remodeling [IMP]
- cloacal septation [IMP]
- ectoderm and mesoderm interaction [IMP]
- embryonic limb morphogenesis [IGI, IMP]
- epidermal cell division [IMP]
- epidermis development [IMP]
- epithelial cell development [IDA, IMP]
- epithelial cell differentiation [IMP]
- establishment of planar polarity [IDA]
- establishment of skin barrier [IMP]
- female genitalia morphogenesis [IMP]
- hair follicle development [IMP]
- hair follicle morphogenesis [IMP]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IMP]
- keratinocyte differentiation [IDA]
- keratinocyte proliferation [IDA]
- mitotic G1 DNA damage checkpoint [IBA]
- morphogenesis of a polarized epithelium [IMP]
- multicellular organismal aging [IMP]
- multicellular organismal development [TAS]
- negative regulation of apoptotic process [IMP]
- negative regulation of cellular senescence [ISO]
- negative regulation of keratinocyte differentiation [IGI, IMP]
- negative regulation of mesoderm development [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP]
- negative regulation of transcription, DNA-templated [ISO]
- neuron apoptotic process [IMP]
- odontogenesis of dentin-containing tooth [IMP]
- organ morphogenesis [IMP]
- pattern specification process [IMP]
- polarized epithelial cell differentiation [IMP]
- positive regulation of Notch signaling pathway [IMP, ISO]
- positive regulation of apoptotic signaling pathway [IDA]
- positive regulation of cell cycle G1/S phase transition [ISO]
- positive regulation of fibroblast apoptotic process [ISO]
- positive regulation of keratinocyte proliferation [IGI]
- positive regulation of mesenchymal cell proliferation [IMP]
- positive regulation of osteoblast differentiation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IBA, IDA, IMP, ISO]
- positive regulation of transcription, DNA-templated [ISO]
- post-anal tail morphogenesis [IMP]
- prostate gland development [IMP]
- prostatic bud formation [IMP]
- protein homotetramerization [ISO]
- proximal/distal pattern formation [IMP]
- regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- regulation of epidermal cell division [IMP]
- regulation of neuron apoptotic process [IBA]
- regulation of nucleic acid-templated transcription [IPI]
- replicative cell aging [ISO]
- response to X-ray [IBA]
- response to gamma radiation [IBA]
- skeletal system development [IMP]
- skin morphogenesis [IMP]
- smooth muscle tissue development [IMP]
- squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [IMP]
- sympathetic nervous system development [IMP]
- transcription from RNA polymerase II promoter [IDA]
- urinary bladder development [IMP]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- WW domain binding [ISO]
- chromatin binding [IDA, ISO]
- damaged DNA binding [IDA]
- double-stranded DNA binding [IBA, ISO]
- identical protein binding [IPI, ISO]
- p53 binding [IBA]
- protein binding [IPI]
- protein domain specific binding [ISO]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IBA, ISO]
- transcription factor binding transcription factor activity [IPI]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- WW domain binding [ISO]
- chromatin binding [IDA, ISO]
- damaged DNA binding [IDA]
- double-stranded DNA binding [IBA, ISO]
- identical protein binding [IPI, ISO]
- p53 binding [IBA]
- protein binding [IPI]
- protein domain specific binding [ISO]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IBA, ISO]
- transcription factor binding transcription factor activity [IPI]
Gene Ontology Cellular Component
Download Curated Data for this Protein
204325
10090
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- Interactors 8
- Interactions 9
- Network