Mus musculus
TWIST1
AA960487, M-Twist, Pde, Ska10, Ska, Twist, bHLHa38, pdt
twist basic helix-loop-helix transcription factor 1
GO Process (54)
GO Function (10)
GO Component (1)
Gene Ontology Biological Process
- aortic valve morphogenesis [IMP, ISO]
- cardiac neural crest cell development involved in outflow tract morphogenesis [IMP]
- cardiac neural crest cell migration involved in outflow tract morphogenesis [IMP]
- cell differentiation [IMP]
- cell proliferation involved in heart valve development [IMP, ISO]
- cellular response to hypoxia [IMP, ISO]
- cranial suture morphogenesis [IMP]
- embryonic camera-type eye formation [ISO]
- embryonic cranial skeleton morphogenesis [IGI, IMP, ISO]
- embryonic digit morphogenesis [IMP]
- embryonic forelimb morphogenesis [IMP]
- embryonic hindlimb morphogenesis [IMP]
- embryonic limb morphogenesis [IMP]
- embryonic skeletal system morphogenesis [IMP]
- endocardial cushion morphogenesis [IMP]
- eyelid development in camera-type eye [ISO]
- hindlimb morphogenesis [IMP]
- in utero embryonic development [IMP]
- mitral valve morphogenesis [IMP]
- negative regulation of DNA damage response, signal transduction by p53 class mediator [ISO]
- negative regulation of apoptotic process [IMP, ISO]
- negative regulation of cell differentiation [IDA]
- negative regulation of cellular senescence [ISO]
- negative regulation of double-strand break repair [ISO]
- negative regulation of histone acetylation [IDA]
- negative regulation of histone phosphorylation [ISO]
- negative regulation of molecular function [IDA]
- negative regulation of osteoblast differentiation [IDA, ISO]
- negative regulation of oxidative phosphorylation uncoupler activity [IDA]
- negative regulation of peroxisome proliferator activated receptor signaling pathway [IDA]
- negative regulation of phosphatidylinositol 3-kinase signaling [ISO]
- negative regulation of sequence-specific DNA binding transcription factor activity [IDA]
- negative regulation of skeletal muscle tissue development [IDA]
- negative regulation of striated muscle tissue development [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- negative regulation of transcription, DNA-templated [IDA]
- negative regulation of tumor necrosis factor production [IGI]
- neural tube closure [IMP]
- neuron migration [IMP]
- ossification [IMP]
- osteoblast differentiation [IMP]
- positive regulation of cell motility [IMP, ISO]
- positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation [IDA]
- positive regulation of epithelial cell proliferation [ISO]
- positive regulation of epithelial to mesenchymal transition [IMP, ISO]
- positive regulation of fatty acid beta-oxidation [ISO]
- positive regulation of gene expression [ISO]
- positive regulation of interleukin-6 secretion [ISO]
- positive regulation of monocyte chemotactic protein-1 production [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISO, TAS]
- positive regulation of transcription regulatory region DNA binding [ISO]
- positive regulation of tumor necrosis factor production [ISO]
- regulation of bone mineralization [ISO]
- transcription from RNA polymerase II promoter [ISO, TAS]
Gene Ontology Molecular Function- E-box binding [IDA, ISO, TAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [TAS]
- bHLH transcription factor binding [ISO]
- protein binding [IPI]
- protein domain specific binding [IPI]
- protein heterodimerization activity [IDA]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [ISO]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription factor binding [IPI, ISO]
- E-box binding [IDA, ISO, TAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [TAS]
- bHLH transcription factor binding [ISO]
- protein binding [IPI]
- protein domain specific binding [IPI]
- protein heterodimerization activity [IDA]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [ISO]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription factor binding [IPI, ISO]
Download Curated Data for this Protein
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- Interactors 110
- Interactions 130
- Network