Mus musculus
MAP3K5
7420452D20Rik, ASK, ASK1, MAPKKK5, Mekk5
mitogen-activated protein kinase kinase kinase 5
GO Process (15)
GO Function (9)
GO Component (2)
Gene Ontology Biological Process
- JNK cascade [ISO]
- MAPK cascade [IDA, ISO]
- activation of MAPK activity [IDA]
- activation of MAPKK activity [IDA, ISO]
- activation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- cellular response to hydrogen peroxide [ISO]
- cellular response to reactive nitrogen species [IMP]
- intrinsic apoptotic signaling pathway in response to oxidative stress [IDA, ISO]
- positive regulation of apoptotic process [IDA, ISO]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of neuron death [ISO]
- positive regulation of protein phosphorylation [ISO]
- programmed necrotic cell death [IMP]
- protein phosphorylation [IDA, ISO]
- regulation of cell death [IGI]
Gene Ontology Molecular Function- ATP binding [ISO]
- MAP kinase kinase kinase activity [IDA, ISO]
- cysteine-type endopeptidase activator activity involved in apoptotic process [ISO]
- magnesium ion binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- protein kinase activity [ISO]
- protein kinase binding [IPI]
- protein phosphatase binding [ISO]
- ATP binding [ISO]
- MAP kinase kinase kinase activity [IDA, ISO]
- cysteine-type endopeptidase activator activity involved in apoptotic process [ISO]
- magnesium ion binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- protein kinase activity [ISO]
- protein kinase binding [IPI]
- protein phosphatase binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
204961
10090
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- Interactors 25
- Interactions 31
- Network