Mus musculus
PYCARD
9130417A21Rik, Asc, CARD5, TMS-1, TNS1, masc
PYD and CARD domain containing
GO Process (54)
GO Function (6)
GO Component (12)
Gene Ontology Biological Process
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- activation of innate immune response [IMP, ISO]
- apoptotic process [ISO]
- cellular response to interleukin-1 [ISO]
- cellular response to lipopolysaccharide [ISO]
- cellular response to tumor necrosis factor [ISO]
- defense response to Gram-negative bacterium [ISO]
- defense response to virus [ISO]
- inflammatory response [IMP]
- interleukin-1 beta production [IGI]
- intrinsic apoptotic signaling pathway by p53 class mediator [ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [ISO]
- macropinocytosis [IMP]
- myeloid dendritic cell activation [ISO]
- myeloid dendritic cell activation involved in immune response [IMP]
- negative regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- negative regulation of NF-kappaB transcription factor activity [ISO]
- negative regulation of interferon-beta production [ISO]
- negative regulation of protein serine/threonine kinase activity [ISO]
- positive regulation of ERK1 and ERK2 cascade [IMP, ISO]
- positive regulation of JNK cascade [ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of T cell activation [ISO]
- positive regulation of T cell migration [IMP]
- positive regulation of actin filament polymerization [IMP]
- positive regulation of activated T cell proliferation [IMP]
- positive regulation of adaptive immune response [ISO]
- positive regulation of antigen processing and presentation of peptide antigen via MHC class II [IMP]
- positive regulation of apoptotic process [ISO]
- positive regulation of chemokine secretion [IMP, ISO]
- positive regulation of cysteine-type endopeptidase activity [ISO]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of defense response to virus by host [IMP]
- positive regulation of extrinsic apoptotic signaling pathway [ISO]
- positive regulation of interferon-gamma production [IMP]
- positive regulation of interleukin-1 beta secretion [IGI, IMP, ISO]
- positive regulation of interleukin-10 secretion [ISO]
- positive regulation of interleukin-6 production [IMP]
- positive regulation of interleukin-6 secretion [ISO]
- positive regulation of interleukin-8 secretion [ISO]
- positive regulation of phagocytosis [IMP]
- positive regulation of release of cytochrome c from mitochondria [ISO]
- positive regulation of sequence-specific DNA binding transcription factor activity [ISO]
- positive regulation of tumor necrosis factor production [ISO]
- regulation of Rac GTPase activity [IMP]
- regulation of apoptotic process [IMP]
- regulation of autophagy [IMP]
- regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- regulation of inflammatory response [IMP]
- regulation of intrinsic apoptotic signaling pathway [ISO]
- regulation of protein stability [IMP]
- regulation of tumor necrosis factor-mediated signaling pathway [ISO]
- response to bacterium [IMP]
- tumor necrosis factor-mediated signaling pathway [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
211743
10090
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- Interactors 11
- Interactions 24
- Network