Mus musculus
DAB2IP
2310011D08Rik, AI480459, Aip1, mKIAA1743, RP23-4L24.1
disabled 2 interacting protein
GO Process (64)
GO Function (21)
GO Component (12)
Gene Ontology Biological Process
- I-kappaB phosphorylation [IMP]
- activation of JUN kinase activity [ISO]
- activation of MAPKKK activity [ISO]
- cell motility involved in cerebral cortex radial glia guided migration [IMP]
- cellular protein catabolic process [ISO]
- cellular response to epidermal growth factor stimulus [ISO]
- cellular response to interleukin-1 [IDA, ISO]
- cellular response to lipopolysaccharide [IDA, ISO]
- cellular response to tumor necrosis factor [IMP, ISO]
- cellular response to vascular endothelial growth factor stimulus [IDA, ISO]
- extrinsic apoptotic signaling pathway via death domain receptors [ISO]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [IMP]
- layer formation in cerebral cortex [IMP]
- negative regulation of ERK1 and ERK2 cascade [ISO]
- negative regulation of G0 to G1 transition [ISO]
- negative regulation of GTPase activity [IMP]
- negative regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- negative regulation of MAP kinase activity [ISO]
- negative regulation of NF-kappaB transcription factor activity [ISO]
- negative regulation of Ras GTPase activity [ISO]
- negative regulation of Ras protein signal transduction [IBA, ISO]
- negative regulation of angiogenesis [IMP, ISO]
- negative regulation of canonical Wnt signaling pathway [ISO]
- negative regulation of catenin import into nucleus [IMP]
- negative regulation of cell growth [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of cyclin catabolic process [ISO]
- negative regulation of endothelial cell migration [IMP, ISO]
- negative regulation of epidermal growth factor receptor signaling pathway [ISO]
- negative regulation of epithelial cell migration [ISO]
- negative regulation of epithelial cell proliferation [ISO]
- negative regulation of epithelial to mesenchymal transition [ISO]
- negative regulation of fibroblast proliferation [IMP]
- negative regulation of phosphatidylinositol 3-kinase activity [ISO]
- negative regulation of phosphatidylinositol 3-kinase signaling [ISO]
- negative regulation of protein phosphorylation [IMP, ISO]
- negative regulation of protein serine/threonine kinase activity [IMP, ISO]
- negative regulation of toll-like receptor 4 signaling pathway [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- negative regulation of vascular endothelial growth factor receptor signaling pathway [IMP, ISO]
- negative regulation of vascular endothelial growth factor signaling pathway [IDA]
- neuron projection morphogenesis [IMP]
- positive regulation of JNK cascade [ISO]
- positive regulation of JUN kinase activity [IMP, ISO]
- positive regulation of MAPK cascade [ISO]
- positive regulation of Ras GTPase activity [IBA, ISO]
- positive regulation of apoptotic process [IMP, ISO]
- positive regulation of apoptotic signaling pathway [ISO]
- positive regulation of cell cycle arrest [ISO]
- positive regulation of dendrite development [IMP]
- positive regulation of neuron migration [IMP]
- positive regulation of neuron projection development [IMP]
- positive regulation of proteasomal protein catabolic process [ISO]
- positive regulation of protein catabolic process [IMP]
- positive regulation of protein serine/threonine kinase activity [IMP, ISO]
- positive regulation of synapse maturation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- regulation of ARF GTPase activity [IMP]
- regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- regulation of p38MAPK cascade [IMP]
- regulation of protein complex assembly [IMP, ISO]
- tube formation [IMP, ISO]
- vascular endothelial growth factor receptor-2 signaling pathway [IMP]
Gene Ontology Molecular Function- 14-3-3 protein binding [ISO]
- Ras GTPase activator activity [IBA, ISO]
- SH3 domain binding [ISO]
- Toll-like receptor 4 binding [IMP]
- death receptor binding [ISO]
- identical protein binding [ISO]
- kinase binding [ISO]
- mitogen-activated protein kinase kinase binding [ISO]
- mitogen-activated protein kinase kinase kinase binding [ISO]
- phosphatidylinositol 3-kinase binding [ISO]
- phosphatidylinositol 3-kinase regulatory subunit binding [ISO]
- phosphatidylinositol-3-phosphate binding [ISO]
- phosphatidylinositol-4-phosphate binding [ISO]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein homodimerization activity [ISO]
- protein kinase binding [ISO]
- protein phosphatase 2A binding [ISO]
- signaling adaptor activity [ISO]
- vascular endothelial growth factor receptor 2 binding [ISO]
- 14-3-3 protein binding [ISO]
- Ras GTPase activator activity [IBA, ISO]
- SH3 domain binding [ISO]
- Toll-like receptor 4 binding [IMP]
- death receptor binding [ISO]
- identical protein binding [ISO]
- kinase binding [ISO]
- mitogen-activated protein kinase kinase binding [ISO]
- mitogen-activated protein kinase kinase kinase binding [ISO]
- phosphatidylinositol 3-kinase binding [ISO]
- phosphatidylinositol 3-kinase regulatory subunit binding [ISO]
- phosphatidylinositol-3-phosphate binding [ISO]
- phosphatidylinositol-4-phosphate binding [ISO]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein homodimerization activity [ISO]
- protein kinase binding [ISO]
- protein phosphatase 2A binding [ISO]
- signaling adaptor activity [ISO]
- vascular endothelial growth factor receptor 2 binding [ISO]
Gene Ontology Cellular Component
- axon [IDA]
- cerebellar mossy fiber [IDA]
- climbing fiber [IDA]
- cytoplasm [IBA, IDA, ISO]
- endocytic vesicle [ISO]
- extracellular vesicular exosome [ISO]
- intracellular [IMP]
- intrinsic component of the cytoplasmic side of the plasma membrane [IBA]
- neuronal cell body [IDA]
- neuronal cell body membrane [IDA]
- parallel fiber [IDA]
- plasma membrane [IDA, ISO]
Download Curated Data for this Protein
213562
10090
Switch View:
- Interactors 30
- Interactions 32
- Network