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Result Summary

Mus musculus

TREM2

TREM-2, Trem2a, Trem2b, Trem2c
triggering receptor expressed on myeloid cells 2
GO Process (16)
GO Function (6)
GO Component (2)

Gene Ontology Biological Process

  • cellular response to lipoteichoic acid [IDA]
  • cellular response to peptidoglycan [IDA]
  • dendritic cell differentiation [ISO]
  • detection of lipopolysaccharide [IDA]
  • detection of lipoteichoic acid [IDA]
  • detection of peptidoglycan [IDA]
  • innate immune response [IC]
  • lipopolysaccharide-mediated signaling pathway [IC]
  • positive regulation of C-C chemokine receptor CCR7 signaling pathway [ISO]
  • positive regulation of CD40 signaling pathway [ISO]
  • positive regulation of ERK1 and ERK2 cascade [ISO]
  • positive regulation of antigen processing and presentation of peptide antigen via MHC class II [ISO]
  • positive regulation of calcium-mediated signaling [ISO]
  • positive regulation of peptidyl-tyrosine phosphorylation [ISO]
  • positive regulation of protein localization to plasma membrane [ISO]
  • signal transduction [ISS]

Gene Ontology Molecular Function

  • lipopolysaccharide binding [IDA]
  • lipoteichoic acid binding [IDA]
  • peptidoglycan binding [IDA]
  • protein binding [IPI]
  • scaffold protein binding [ISO]
  • transmembrane signaling receptor activity [ISS]

Gene Ontology Cellular Component

  • integral component of membrane [ISO]
  • intracellular membrane-bounded organelle [ISO]
CRISPR Database VEGA MGI Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl
219923
10090

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