Mus musculus
BBC3
PUMA, PUMA/JFY1
BCL2 binding component 3
GO Process (24)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
- activation of cysteine-type endopeptidase activity involved in apoptotic process [ISO, ISS]
- apoptotic signaling pathway [ISO]
- cellular response to DNA damage stimulus [IGI]
- cellular response to ionizing radiation [IGI]
- determination of adult lifespan [IGI]
- execution phase of apoptosis [ISO, ISS]
- intrinsic apoptotic signaling pathway by p53 class mediator [ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IMP]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [IMP]
- negative regulation of cell growth [ISO]
- negative regulation of endoplasmic reticulum calcium ion concentration [ISO]
- negative regulation of growth [ISO, ISS]
- positive regulation of apoptotic process [IMP]
- positive regulation of cysteine-type endopeptidase activity [IMP]
- positive regulation of intrinsic apoptotic signaling pathway [ISO]
- positive regulation of neuron apoptotic process [IMP]
- positive regulation of protein homooligomerization [ISO]
- positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [IMP, ISO]
- positive regulation of release of cytochrome c from mitochondria [ISO]
- positive regulation of thymocyte apoptotic process [IGI]
- release of cytochrome c from mitochondria [ISO, ISS]
- release of sequestered calcium ion into cytosol [ISO]
- response to endoplasmic reticulum stress [IDA, ISO]
- toxin transport [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
228430
10090
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- Interactors 3
- Interactions 3
- Network