Mus musculus
NLRP3
AGTAVPRL, AII/AVP, Cias1, FCAS, FCU, MWS, Mmig1, NALP3, Pypaf1, RP23-210M6.4
NLR family, pyrin domain containing 3
GO Process (17)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- NLRP3 inflammasome complex assembly [IMP]
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- cellular response to lipopolysaccharide [ISO]
- defense response to virus [IMP]
- inflammatory response [ISO]
- interleukin-1 beta production [IMP]
- interleukin-1 secretion [IMP]
- interleukin-18 production [IMP]
- negative regulation of NF-kappaB import into nucleus [ISO]
- negative regulation of NF-kappaB transcription factor activity [ISO]
- negative regulation of acute inflammatory response [ISO]
- negative regulation of inflammatory response [ISO]
- negative regulation of interleukin-1 beta secretion [ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of interleukin-1 beta secretion [IGI, ISO]
- regulation of inflammatory response [IMP]
Gene Ontology Molecular Function
Download Curated Data for this Protein
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- Interactors 54
- Interactions 83
- Network