Mus musculus
NOD2
ACUG, BLAU, CD, Card15, F830032C23Rik, IBD1, Nlrc2
nucleotide-binding oligomerization domain containing 2
GO Process (71)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- activation of MAPK activity involved in innate immune response [IDA]
- activation of immune response [IMP]
- cellular response to muramyl dipeptide [ISO]
- cellular response to peptidoglycan [IMP]
- cytokine production involved in immune response [ISO]
- defense response [TAS]
- defense response to Gram-positive bacterium [IGI, IMP]
- defense response to bacterium [ISO]
- detection of bacterium [ISO]
- detection of biotic stimulus [TAS]
- detection of muramyl dipeptide [ISO]
- immunoglobulin production involved in immunoglobulin mediated immune response [IMP]
- inflammatory response [TAS]
- innate immune response [ISO]
- innate immune response in mucosa [IMP]
- intracellular signal transduction [ISO]
- macrophage inflammatory protein-1 alpha production [IMP]
- maintenance of gastrointestinal epithelium [ISO]
- negative regulation of NF-kappaB transcription factor activity [IMP]
- negative regulation of T cell mediated immunity [IMP]
- negative regulation of growth of symbiont in host [IMP]
- negative regulation of inflammatory response to antigenic stimulus [IMP]
- negative regulation of interferon-gamma production [IMP]
- negative regulation of interleukin-12 production [IDA, IMP]
- negative regulation of interleukin-18 production [IMP]
- negative regulation of interleukin-2 production [IMP]
- negative regulation of macrophage apoptotic process [IDA]
- negative regulation of toll-like receptor 2 signaling pathway [IMP]
- negative regulation of tumor necrosis factor production [IMP]
- nucleotide-binding oligomerization domain containing 2 signaling pathway [IMP, ISO]
- positive regulation of B cell activation [ISO]
- positive regulation of ERK1 and ERK2 cascade [IDA]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IDA, ISO]
- positive regulation of JNK cascade [IDA, ISO]
- positive regulation of MAPK cascade [IMP]
- positive regulation of NF-kappaB transcription factor activity [IMP, ISO]
- positive regulation of Notch signaling pathway [IDA]
- positive regulation of antibacterial peptide biosynthetic process [IDA]
- positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [IMP]
- positive regulation of cell proliferation [ISO]
- positive regulation of dendritic cell antigen processing and presentation [IMP]
- positive regulation of dendritic cell cytokine production [ISO]
- positive regulation of epithelial cell proliferation [IMP]
- positive regulation of humoral immune response mediated by circulating immunoglobulin [IMP]
- positive regulation of innate immune response [IMP]
- positive regulation of interleukin-1 beta production [ISO]
- positive regulation of interleukin-1 beta secretion [IDA, ISO]
- positive regulation of interleukin-10 production [IMP]
- positive regulation of interleukin-12 production [IDA, IMP]
- positive regulation of interleukin-17 production [ISO]
- positive regulation of interleukin-6 production [IDA, IGI, IMP, ISO]
- positive regulation of nitric-oxide synthase biosynthetic process [IMP]
- positive regulation of oxidoreductase activity [IDA]
- positive regulation of peptidyl-tyrosine phosphorylation [IMP]
- positive regulation of phagocytosis [IMP]
- positive regulation of phosphatidylinositol 3-kinase activity [IMP]
- positive regulation of prostaglandin-E synthase activity [IDA]
- positive regulation of prostaglandin-endoperoxide synthase activity [IDA]
- positive regulation of protein ubiquitination [IDA]
- positive regulation of stress-activated MAPK cascade [IDA, ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of tumor necrosis factor production [IDA, IGI, IMP, ISO]
- positive regulation of type 2 immune response [ISO]
- protein oligomerization [TAS]
- regulation of inflammatory response [IMP]
- regulation of neutrophil chemotaxis [IMP]
- response to exogenous dsRNA [IMP]
- response to lipopolysaccharide [IMP]
- response to muramyl dipeptide [IDA, IMP, ISO]
- response to peptidoglycan [IDA, IMP]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
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