BioGRID4.4
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Result Summary

Mus musculus

NLRC4

9530011P19Rik, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, Card12, IPAF
NLR family, CARD domain containing 4
GO Process (19)
GO Function (5)
GO Component (5)

Gene Ontology Biological Process

  • activation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
  • activation of innate immune response [IMP]
  • cytokinesis [IBA]
  • defense response to bacterium [IMP, ISO]
  • detection of bacterium [IMP, ISO]
  • inflammatory response [IMP]
  • inhibition of cysteine-type endopeptidase activity involved in apoptotic process [IBA]
  • interleukin-1 beta secretion [IMP, ISO]
  • negative regulation of apoptotic process [IBA]
  • positive regulation of NF-kappaB transcription factor activity [ISO]
  • positive regulation of apoptotic process [ISO]
  • protein homooligomerization [IDA]
  • protein ubiquitination [IBA]
  • pyroptosis [IMP]
  • regulation of apoptotic process [IMP]
  • regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
  • regulation of neuron apoptotic process [IBA]
  • regulation of signal transduction [IBA]
  • spindle assembly involved in mitosis [IBA]

Gene Ontology Molecular Function

  • ATP binding [ISO]
  • cysteine-type endopeptidase inhibitor activity [IBA]
  • identical protein binding [ISO]
  • protein homodimerization activity [ISO]
  • ubiquitin-protein transferase activity [IBA]

Gene Ontology Cellular Component

  • IPAF inflammasome complex [IDA]
  • cell [IMP]
  • cytosol [IDA]
  • nucleus [IBA]
  • spindle microtubule [IBA]
CRISPR Database MGI Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl
234588
10090

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