Mus musculus
EP300
A430090G16, A730011L11, KAT3B, p300, p300 HAT
E1A binding protein p300
GO Process (58)
GO Function (35)
GO Component (7)
Gene Ontology Biological Process
- N-terminal peptidyl-lysine acetylation [ISO, ISS]
- apoptotic process [ISO, ISS]
- cartilage development [NAS]
- circadian rhythm [IDA]
- heart development [IMP]
- histone H2B acetylation [ISO]
- histone H3 acetylation [ISO]
- histone H4 acetylation [ISO, ISS]
- histone acetylation [ISO]
- internal peptidyl-lysine acetylation [ISO]
- internal protein amino acid acetylation [ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [ISO]
- lung development [IMP]
- negative regulation of cell death [ISO]
- negative regulation of cellular metabolic process [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of miRNA metabolic process [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- organ morphogenesis [IMP]
- positive regulation by host of viral transcription [ISO]
- positive regulation of DNA binding [ISO]
- positive regulation of axon extension [ISO]
- positive regulation of cell death [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cell size [ISO]
- positive regulation of cellular metabolic process [ISO]
- positive regulation of collagen biosynthetic process [ISO]
- positive regulation of gene expression [ISO]
- positive regulation of glycoprotein biosynthetic process [ISO]
- positive regulation of histone acetylation [ISO]
- positive regulation of muscle atrophy [ISO]
- positive regulation of protein acetylation [ISO]
- positive regulation of protein binding [IDA]
- positive regulation of protein import into nucleus, translocation [ISO]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of protein secretion [ISO]
- positive regulation of proteolysis [ISO]
- positive regulation of sarcomere organization [ISO]
- positive regulation of sequence-specific DNA binding transcription factor activity [IDA, ISO, ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, ISO]
- positive regulation of transcription, DNA-templated [IDA]
- positive regulation of translation [ISO]
- protein kinase B signaling [ISO]
- protein-DNA complex assembly [ISO]
- regulation of androgen receptor signaling pathway [ISO]
- regulation of angiotensin metabolic process [ISO]
- regulation of nucleic acid-templated transcription [IMP]
- regulation of transcription, DNA-templated [IDA, ISO, ISS]
- regulation of tubulin deacetylation [ISO]
- response to calcium ion [ISO]
- response to dexamethasone [ISO]
- response to drug [ISO]
- response to estrogen [ISO]
- response to glucose [ISO]
- response to hypoxia [ISO, ISS]
- skeletal muscle tissue development [IMP]
- somitogenesis [IGI]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- DNA binding [IDA, ISO, ISS]
- NF-kappaB binding [ISO]
- RNA polymerase II activating transcription factor binding [IPI, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter sequence-specific DNA binding [IDA]
- RNA polymerase II transcription factor binding [IPI]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- SMAD binding [ISO]
- acetyltransferase activity [IDA, ISO, ISS]
- activating transcription factor binding [ISO]
- androgen receptor binding [ISO]
- antigen binding [ISO]
- bHLH transcription factor binding [ISO]
- beta-catenin binding [ISO]
- chromatin DNA binding [IDA, ISO]
- chromatin binding [ISO]
- core promoter binding [ISO]
- core promoter proximal region DNA binding [ISO]
- glucocorticoid receptor binding [ISO]
- histone acetyltransferase activity [ISO, ISS]
- lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [ISO]
- mitogen-activated protein kinase binding [ISO]
- nuclear hormone receptor binding [ISO]
- p53 binding [IPI, ISO]
- peroxisome proliferator activated receptor binding [ISO]
- pre-mRNA intronic binding [IDA]
- protein C-terminus binding [ISO]
- protein antigen binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein kinase binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription coactivator activity [IMP, ISO, ISS]
- transcription factor binding [IPI, ISO]
- transferase activity, transferring acyl groups [ISO]
- DNA binding [IDA, ISO, ISS]
- NF-kappaB binding [ISO]
- RNA polymerase II activating transcription factor binding [IPI, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter sequence-specific DNA binding [IDA]
- RNA polymerase II transcription factor binding [IPI]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- SMAD binding [ISO]
- acetyltransferase activity [IDA, ISO, ISS]
- activating transcription factor binding [ISO]
- androgen receptor binding [ISO]
- antigen binding [ISO]
- bHLH transcription factor binding [ISO]
- beta-catenin binding [ISO]
- chromatin DNA binding [IDA, ISO]
- chromatin binding [ISO]
- core promoter binding [ISO]
- core promoter proximal region DNA binding [ISO]
- glucocorticoid receptor binding [ISO]
- histone acetyltransferase activity [ISO, ISS]
- lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [ISO]
- mitogen-activated protein kinase binding [ISO]
- nuclear hormone receptor binding [ISO]
- p53 binding [IPI, ISO]
- peroxisome proliferator activated receptor binding [ISO]
- pre-mRNA intronic binding [IDA]
- protein C-terminus binding [ISO]
- protein antigen binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein kinase binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription coactivator activity [IMP, ISO, ISS]
- transcription factor binding [IPI, ISO]
- transferase activity, transferring acyl groups [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
236625
10090
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- Interactors 94
- Interactions 126
- Network
- PTM Sites 6