Main protease of SARS-CoV-2 serves as a bifunctional molecule in restricting type I interferon antiviral signaling.
Mesh Terms:
Adaptor Proteins, Signal Transducing, Betacoronavirus, Cell Line, Tumor, Coronavirus 3C Proteases, Cysteine Endopeptidases, Cytokines, DEAD Box Protein 58, Epithelial Cells, Gene Expression Regulation, Hepatocytes, Host-Pathogen Interactions, Humans, Interferon Regulatory Factor-3, Interferon-alpha, Interferon-beta, Protein Serine-Threonine Kinases, RNA-Binding Proteins, Receptors, Immunologic, SARS-CoV-2, STAT1 Transcription Factor, Signal Transduction, Ubiquitins, Viral Nonstructural Proteins
Adaptor Proteins, Signal Transducing, Betacoronavirus, Cell Line, Tumor, Coronavirus 3C Proteases, Cysteine Endopeptidases, Cytokines, DEAD Box Protein 58, Epithelial Cells, Gene Expression Regulation, Hepatocytes, Host-Pathogen Interactions, Humans, Interferon Regulatory Factor-3, Interferon-alpha, Interferon-beta, Protein Serine-Threonine Kinases, RNA-Binding Proteins, Receptors, Immunologic, SARS-CoV-2, STAT1 Transcription Factor, Signal Transduction, Ubiquitins, Viral Nonstructural Proteins
Signal Transduct Target Ther
Date: Oct. 06, 2020
PubMed ID: 33024073
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