Rattus norvegicus
BCL2
Bcl-2
B-cell CLL/lymphoma 2
GO Process (156)
GO Function (14)
GO Component (14)
Gene Ontology Biological Process
- B cell differentiation [ISO]
- B cell homeostasis [ISO]
- B cell lineage commitment [ISO]
- B cell proliferation [ISO]
- B cell receptor signaling pathway [ISO]
- CD8-positive, alpha-beta T cell lineage commitment [ISO]
- T cell differentiation [ISO]
- T cell differentiation in thymus [ISO]
- T cell homeostasis [ISO]
- T cell lineage commitment [ISO]
- actin filament organization [ISO]
- aging [IEP]
- apoptotic mitochondrial changes [ISO]
- apoptotic process [IEP, ISO, TAS]
- axon regeneration [ISO]
- axonogenesis [ISO]
- behavioral fear response [ISO]
- brain development [IEP]
- branching involved in ureteric bud morphogenesis [ISO]
- cell aging [ISO]
- cell growth [ISO]
- cell morphogenesis [ISO]
- cell proliferation [ISO]
- cellular calcium ion homeostasis [ISO]
- cellular response to DNA damage stimulus [ISO]
- cellular response to glucose starvation [ISO]
- cellular response to hypoxia [ISO]
- cellular response to organic substance [ISO]
- cochlear nucleus development [ISO]
- defense response to virus [ISO]
- developmental growth [ISO]
- developmental pigmentation [ISO]
- digestive tract morphogenesis [ISO]
- ear development [ISO]
- endoplasmic reticulum calcium ion homeostasis [ISO]
- extrinsic apoptotic signaling pathway in absence of ligand [IBA, ISO]
- extrinsic apoptotic signaling pathway via death domain receptors [ISO]
- focal adhesion assembly [ISO]
- gland morphogenesis [ISO]
- glial cell apoptotic process [IEP]
- glomerulus development [ISO]
- growth [ISO]
- hair follicle morphogenesis [ISO]
- hemopoiesis [ISO]
- homeostasis of number of cells within a tissue [ISO]
- immune system development [ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage [IBA]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [ISO]
- intrinsic apoptotic signaling pathway in response to oxidative stress [ISO]
- kidney development [ISO]
- leukocyte homeostasis [ISO]
- lymphocyte homeostasis [ISO]
- lymphoid progenitor cell differentiation [ISO]
- male gonad development [ISO]
- melanin metabolic process [ISO]
- melanocyte differentiation [ISO]
- mesenchymal cell development [ISO]
- metanephros development [ISO]
- negative regulation of G1/S transition of mitotic cell cycle [ISO]
- negative regulation of anoikis [ISO]
- negative regulation of apoptotic process [IDA, IMP, ISO]
- negative regulation of apoptotic signaling pathway [ISO]
- negative regulation of calcium ion transport into cytosol [ISO]
- negative regulation of cell growth [ISO]
- negative regulation of cell migration [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of cellular pH reduction [ISO]
- negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [ISO]
- negative regulation of intrinsic apoptotic signaling pathway [IBA, ISO]
- negative regulation of mitotic cell cycle [ISO]
- negative regulation of myeloid cell apoptotic process [ISO]
- negative regulation of neuron apoptotic process [ISO]
- negative regulation of ossification [ISO]
- negative regulation of osteoblast proliferation [ISO]
- negative regulation of retinal cell programmed cell death [ISO]
- neuron apoptotic process [ISO]
- oligodendrocyte differentiation [IEP]
- oocyte development [ISO]
- organ growth [ISO]
- organ morphogenesis [ISO]
- ossification [ISO]
- ovarian follicle development [IEP, ISO]
- peptidyl-serine phosphorylation [ISO]
- peptidyl-threonine phosphorylation [ISO]
- pigment granule organization [ISO]
- pigmentation [ISO]
- positive regulation of B cell proliferation [ISO]
- positive regulation of catalytic activity [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of developmental pigmentation [ISO]
- positive regulation of melanocyte differentiation [ISO]
- positive regulation of multicellular organism growth [ISO]
- positive regulation of neuron maturation [ISO]
- positive regulation of peptidyl-serine phosphorylation [ISO]
- positive regulation of skeletal muscle fiber development [ISO]
- positive regulation of smooth muscle cell migration [ISO]
- post-embryonic development [ISO]
- protein dephosphorylation [ISO]
- protein polyubiquitination [ISO]
- reactive oxygen species metabolic process [ISO]
- regulation of apoptotic process [ISO]
- regulation of calcium ion transport [ISO]
- regulation of catalytic activity [ISO]
- regulation of cell cycle [ISO]
- regulation of cell-matrix adhesion [ISO]
- regulation of developmental pigmentation [ISO]
- regulation of gene expression [ISO]
- regulation of glycoprotein biosynthetic process [ISO]
- regulation of mitochondrial membrane permeability [ISO, ISS]
- regulation of mitochondrial membrane potential [ISO, ISS]
- regulation of nitrogen utilization [ISO]
- regulation of programmed cell death [ISO]
- regulation of protein heterodimerization activity [ISO]
- regulation of protein homodimerization activity [ISO]
- regulation of protein localization [ISO]
- regulation of protein stability [ISO]
- regulation of transmembrane transporter activity [ISO]
- regulation of viral genome replication [ISO]
- release of cytochrome c from mitochondria [ISO, ISS]
- renal system process [ISO]
- response to L-ascorbic acid [IEP]
- response to UV-B [ISO]
- response to aluminum ion [IEP]
- response to cAMP [IEP]
- response to caffeine [IEP]
- response to copper ion [IEP]
- response to corticosterone [IEP]
- response to cytokine [IEP, ISO]
- response to drug [IEP, ISO]
- response to electrical stimulus [IEP]
- response to estrogen [IEP]
- response to ethanol [IEP]
- response to folic acid [IEP]
- response to gamma radiation [ISO]
- response to glucocorticoid [ISO]
- response to heat [IEP]
- response to hydrogen peroxide [ISO]
- response to hypoxia [IEP]
- response to inorganic substance [IEP]
- response to insulin [IEP]
- response to iron ion [ISO]
- response to ischemia [ISO]
- response to nicotine [IEP, ISO]
- response to nutrient [IEP]
- response to organic cyclic compound [IEP]
- response to organic substance [IEP]
- response to oxidative stress [ISO]
- response to peptide hormone [IEP]
- response to steroid hormone [ISO]
- response to toxic substance [ISO]
- single organismal cell-cell adhesion [ISO]
- spleen development [ISO]
- thymus development [ISO]
- transmembrane transport [ISO]
- ureteric bud development [ISO]
Gene Ontology Molecular Function- BH domain binding [IPI]
- BH3 domain binding [ISO]
- channel activity [ISO]
- channel inhibitor activity [ISO]
- identical protein binding [ISO]
- protease binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [IPI, ISO]
- protein homodimerization activity [IBA, ISO]
- protein phosphatase 2A binding [ISO]
- protein phosphatase binding [ISO]
- sequence-specific DNA binding [ISO]
- transcription factor binding [ISO]
- ubiquitin protein ligase binding [ISO]
- BH domain binding [IPI]
- BH3 domain binding [ISO]
- channel activity [ISO]
- channel inhibitor activity [ISO]
- identical protein binding [ISO]
- protease binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [IPI, ISO]
- protein homodimerization activity [IBA, ISO]
- protein phosphatase 2A binding [ISO]
- protein phosphatase binding [ISO]
- sequence-specific DNA binding [ISO]
- transcription factor binding [ISO]
- ubiquitin protein ligase binding [ISO]
Gene Ontology Cellular Component
- cell [ISO]
- cytoplasm [IDA, ISO]
- cytosol [ISO]
- endoplasmic reticulum [ISO]
- endoplasmic reticulum membrane [ISO]
- intracellular [ISO]
- membrane [ISO]
- mitochondrial membrane [ISO]
- mitochondrial outer membrane [IBA, ISO]
- mitochondrion [IDA, ISO]
- myelin sheath [ISO]
- nuclear membrane [ISO]
- nucleus [ISO]
- pore complex [ISO]
Download Curated Data for this Protein
246412
10116
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