Rattus norvegicus
PDGFRB
PDGFR-1
platelet derived growth factor receptor, beta polypeptide
GO Process (66)
GO Function (13)
GO Component (9)
Gene Ontology Biological Process
- adrenal gland development [ISO]
- aorta morphogenesis [ISO]
- cardiac myofibril assembly [ISO, ISS]
- cell chemotaxis [ISO, ISS]
- cell migration [ISO, ISS]
- cell migration involved in coronary angiogenesis [ISO, ISS]
- cell migration involved in vasculogenesis [ISO, ISS]
- cellular response to platelet-derived growth factor stimulus [IDA, TAS]
- glycosaminoglycan biosynthetic process [IMP]
- hemopoiesis [ISO, ISS]
- in utero embryonic development [ISO]
- inner ear development [IEP]
- intracellular signal transduction [IMP]
- kidney development [ISO]
- metanephric S-shaped body morphogenesis [IEP]
- metanephric comma-shaped body morphogenesis [IEP]
- metanephric glomerular capillary formation [ISO, ISS]
- metanephric glomerular mesangial cell proliferation involved in metanephros development [ISO, ISS]
- metanephric glomerulus morphogenesis [IEP]
- metanephric mesenchymal cell migration [IDA]
- metanephric mesenchyme development [IEP]
- negative regulation of apoptotic process [IMP]
- nitrogen compound metabolic process [ISO]
- peptidyl-tyrosine phosphorylation [ISO, ISS]
- phosphatidylinositol metabolic process [ISO, ISS]
- phosphatidylinositol-mediated signaling [ISO, ISS]
- phosphorylation [ISO]
- platelet-derived growth factor receptor signaling pathway [ISO]
- platelet-derived growth factor receptor-beta signaling pathway [ISO]
- positive regulation of DNA biosynthetic process [ISO, ISS]
- positive regulation of ERK1 and ERK2 cascade [ISO, ISS]
- positive regulation of MAP kinase activity [ISO, ISS]
- positive regulation of calcium ion import [ISO, ISS]
- positive regulation of cell migration [ISO, ISS]
- positive regulation of cell proliferation [IMP, ISO]
- positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [ISO]
- positive regulation of chemotaxis [ISO, ISS]
- positive regulation of collagen biosynthetic process [IMP]
- positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway [ISO, ISS]
- positive regulation of mitosis [ISO, ISS]
- positive regulation of phosphatidylinositol 3-kinase activity [ISO, ISS]
- positive regulation of phosphatidylinositol 3-kinase signaling [ISO, ISS]
- positive regulation of phospholipase C activity [ISO, ISS]
- positive regulation of phosphoprotein phosphatase activity [ISO]
- positive regulation of reactive oxygen species metabolic process [ISO, ISS]
- positive regulation of smooth muscle cell migration [ISO, ISS]
- positive regulation of smooth muscle cell proliferation [ISO, ISS]
- protein autophosphorylation [ISO, ISS]
- regulation of actin cytoskeleton organization [ISO]
- regulation of peptidyl-tyrosine phosphorylation [ISO]
- response to estradiol [IEP]
- response to estrogen [IEP]
- response to fluid shear stress [IEP]
- response to hydrogen peroxide [IEP]
- response to hyperoxia [IEP]
- response to lipid [IEP]
- response to organic cyclic compound [IEP]
- response to retinoic acid [IEP]
- response to toxic substance [IEP]
- retina vasculature development in camera-type eye [ISO, ISS]
- signal transduction [ISO]
- skeletal system morphogenesis [ISO]
- smooth muscle cell chemotaxis [ISO]
- smooth muscle tissue development [ISO]
- tissue homeostasis [ISO]
- wound healing [IEP]
Gene Ontology Molecular Function- kinase activity [ISO]
- phosphatidylinositol 3-kinase binding [IPI]
- platelet-derived growth factor beta-receptor activity [ISO, ISS]
- platelet-derived growth factor binding [ISO]
- platelet-derived growth factor receptor binding [ISO]
- platelet-derived growth factor-activated receptor activity [IDA, TAS]
- protein binding [IPI]
- protein kinase activity [TAS]
- protein kinase binding [ISO]
- protein tyrosine kinase activity [IDA, ISO, TAS]
- receptor binding [ISO]
- signal transducer activity [ISO]
- vascular endothelial growth factor binding [ISO]
- kinase activity [ISO]
- phosphatidylinositol 3-kinase binding [IPI]
- platelet-derived growth factor beta-receptor activity [ISO, ISS]
- platelet-derived growth factor binding [ISO]
- platelet-derived growth factor receptor binding [ISO]
- platelet-derived growth factor-activated receptor activity [IDA, TAS]
- protein binding [IPI]
- protein kinase activity [TAS]
- protein kinase binding [ISO]
- protein tyrosine kinase activity [IDA, ISO, TAS]
- receptor binding [ISO]
- signal transducer activity [ISO]
- vascular endothelial growth factor binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
246767
10116
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- Interactors 2
- Interactions 2
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