Rattus norvegicus
PTPRC
CD45, L-CA, Lca, RT7, T200
protein tyrosine phosphatase, receptor type, C
GO Process (47)
GO Function (7)
GO Component (12)
Gene Ontology Biological Process
- B cell differentiation [ISO]
- B cell proliferation [ISO, ISS]
- B cell receptor signaling pathway [ISO, ISS]
- T cell differentiation [ISO, ISS]
- T cell proliferation [ISO]
- T cell receptor signaling pathway [ISO, ISS]
- activation of MAPK activity [ISO]
- bone marrow development [ISO]
- cell cycle phase transition [ISO]
- defense response to virus [ISO, ISS]
- dephosphorylation [ISO, ISS]
- hematopoietic progenitor cell differentiation [ISO]
- heterotypic cell-cell adhesion [ISO]
- immunoglobulin biosynthetic process [ISO]
- leukocyte cell-cell adhesion [ISO]
- negative regulation of T cell mediated cytotoxicity [ISO, ISS]
- negative regulation of cell adhesion involved in substrate-bound cell migration [ISO]
- negative regulation of cytokine-mediated signaling pathway [ISO, ISS]
- negative regulation of peptidyl-tyrosine phosphorylation [ISO]
- negative regulation of protein autophosphorylation [ISO]
- negative regulation of protein kinase activity [ISO, ISS]
- negative thymic T cell selection [ISO]
- peptidyl-tyrosine dephosphorylation [ISO, ISS, TAS]
- positive regulation of B cell proliferation [ISO]
- positive regulation of MAPK cascade [ISO]
- positive regulation of T cell differentiation [ISO]
- positive regulation of T cell mediated cytotoxicity [ISO]
- positive regulation of T cell mediated immunity [ISO]
- positive regulation of T cell proliferation [ISO, ISS]
- positive regulation of alpha-beta T cell proliferation [ISO]
- positive regulation of antigen receptor-mediated signaling pathway [ISO, ISS]
- positive regulation of extrinsic apoptotic signaling pathway [ISO]
- positive regulation of gamma-delta T cell differentiation [ISO]
- positive regulation of hematopoietic stem cell migration [ISO]
- positive regulation of humoral immune response mediated by circulating immunoglobulin [ISO]
- positive regulation of isotype switching to IgG isotypes [ISO]
- positive regulation of stem cell proliferation [ISO]
- positive thymic T cell selection [ISO]
- protein dephosphorylation [ISO, ISS, TAS]
- regulation of B cell differentiation [ISO]
- regulation of B cell receptor signaling pathway [ISO]
- regulation of cell cycle [ISO, ISS]
- regulation of extrinsic apoptotic signaling pathway [ISO]
- regulation of humoral immune response mediated by circulating immunoglobulin [ISO]
- release of sequestered calcium ion into cytosol [ISO, ISS]
- response to gamma radiation [IDA]
- stem cell development [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell periphery [ISO]
- cell surface [IDA]
- cytoplasmic side of plasma membrane [TAS]
- cytosol [ISO]
- external side of plasma membrane [ISO]
- extracellular vesicular exosome [ISO]
- focal adhesion [ISO, ISS]
- integral component of membrane [IDA]
- integral component of plasma membrane [IDA]
- intracellular [ISO]
- membrane [ISO]
- plasma membrane [ISO]
Download Curated Data for this Protein
246829
10116
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- Interactions 1
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