Rattus norvegicus
BAX
Bcl2-associated X protein
GO Process (112)
GO Function (11)
GO Component (17)
Gene Ontology Biological Process
- B cell apoptotic process [ISO, ISS]
- B cell homeostasis [ISO]
- B cell homeostatic proliferation [ISO]
- B cell negative selection [ISO]
- B cell receptor apoptotic signaling pathway [ISO]
- Sertoli cell proliferation [ISO]
- T cell homeostatic proliferation [ISO]
- activation of cysteine-type endopeptidase activity involved in apoptotic process [ISO, ISS]
- activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [ISO, ISS, TAS]
- activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [ISO]
- apoptotic mitochondrial changes [ISO, ISS]
- apoptotic process [IEP, IMP, ISO]
- apoptotic process involved in embryonic digit morphogenesis [ISO]
- apoptotic process involved in patterning of blood vessels [ISO]
- apoptotic signaling pathway [ISO, ISS]
- blood vessel remodeling [ISO]
- brain development [IEP]
- cell proliferation [ISO]
- cellular respiration [IDA]
- cellular response to DNA damage stimulus [ISO]
- cellular response to UV [ISO]
- cellular response to organic substance [ISO]
- cerebral cortex development [ISO]
- development of secondary sexual characteristics [ISO]
- ectopic germ cell programmed cell death [ISO]
- establishment or maintenance of transmembrane electrochemical gradient [ISO, ISS]
- extrinsic apoptotic signaling pathway [ISO]
- extrinsic apoptotic signaling pathway in absence of ligand [IBA, ISO]
- extrinsic apoptotic signaling pathway via death domain receptors [ISO]
- fertilization [ISO]
- germ cell development [ISO]
- glial cell apoptotic process [IEP]
- glycosphingolipid metabolic process [ISO]
- homeostasis of number of cells [ISO]
- homeostasis of number of cells within a tissue [ISO]
- hypothalamus development [ISO]
- inner mitochondrial membrane organization [IDA]
- intrinsic apoptotic signaling pathway [ISO, ISS]
- intrinsic apoptotic signaling pathway by p53 class mediator [ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage [IBA, ISO]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [ISO, ISS]
- kidney development [ISO]
- leukocyte homeostasis [ISO]
- limb morphogenesis [ISO]
- male gonad development [ISO]
- mitochondrial fragmentation involved in apoptotic process [ISO, ISS]
- mitochondrial fusion [IBA, ISO, ISS]
- mitochondrion morphogenesis [ISO]
- myeloid cell homeostasis [ISO]
- negative regulation of apoptotic signaling pathway [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of endoplasmic reticulum calcium ion concentration [ISO]
- negative regulation of fibroblast proliferation [ISO]
- negative regulation of neuron apoptotic process [ISO]
- negative regulation of peptidyl-serine phosphorylation [ISO]
- negative regulation of protein binding [ISO, ISS]
- nervous system development [ISO]
- neuron apoptotic process [ISO]
- neuron migration [ISO]
- odontogenesis of dentin-containing tooth [ISO]
- outer mitochondrial membrane organization [IDA]
- ovarian follicle development [IEP, ISO]
- positive regulation of B cell apoptotic process [ISO]
- positive regulation of apoptotic DNA fragmentation [ISO]
- positive regulation of apoptotic process [IMP, ISO, ISS]
- positive regulation of apoptotic process involved in mammary gland involution [ISO]
- positive regulation of calcium ion transport into cytosol [ISO]
- positive regulation of developmental pigmentation [ISO]
- positive regulation of endoplasmic reticulum unfolded protein response [ISO, ISS]
- positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [ISO]
- positive regulation of intrinsic apoptotic signaling pathway [ISO, ISS]
- positive regulation of mitochondrial membrane permeability involved in apoptotic process [ISO]
- positive regulation of neuron apoptotic process [ISO, ISS]
- positive regulation of protein oligomerization [ISO, ISS]
- positive regulation of release of cytochrome c from mitochondria [ISO, ISS]
- positive regulation of release of sequestered calcium ion into cytosol [ISO]
- post-embryonic camera-type eye morphogenesis [ISO]
- post-embryonic development [ISO]
- protein homooligomerization [ISO]
- protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [ISO]
- protein oligomerization [ISO]
- regulation of cell cycle [ISO]
- regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- regulation of mammary gland epithelial cell proliferation [ISO]
- regulation of mitochondrial membrane permeability involved in apoptotic process [ISO]
- regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [ISO]
- regulation of mitochondrial membrane potential [ISO, ISS]
- regulation of neuron apoptotic process [ISO]
- regulation of nitrogen utilization [ISO]
- regulation of protein heterodimerization activity [ISO]
- regulation of protein homodimerization activity [ISO, ISS]
- release of cytochrome c from mitochondria [IBA, ISO]
- release of matrix enzymes from mitochondria [ISO, ISS]
- response to axon injury [ISO]
- response to cocaine [IEP]
- response to copper ion [IEP]
- response to corticosterone [IEP]
- response to drug [IEP]
- response to gamma radiation [ISO]
- response to ionizing radiation [ISO]
- response to salt stress [ISO]
- response to toxic substance [ISO, ISS]
- response to wounding [ISO]
- retina development in camera-type eye [ISO]
- retinal cell apoptotic process [ISO, ISS]
- retinal cell programmed cell death [ISO]
- sex differentiation [ISO]
- spermatid differentiation [ISO]
- spermatogenesis [ISO]
- thymocyte apoptotic process [ISO]
- transformed cell apoptotic process [ISO, ISS]
- vagina development [ISO]
Gene Ontology Molecular Function- BH domain binding [IPI]
- BH3 domain binding [ISO, ISS]
- channel activity [IBA, ISO, ISS]
- chaperone binding [IPI]
- heat shock protein binding [IPI]
- identical protein binding [ISO]
- lipid binding [ISO, ISS]
- protein binding [IPI]
- protein complex binding [IPI]
- protein heterodimerization activity [IPI, ISO]
- protein homodimerization activity [IBA, ISO]
- BH domain binding [IPI]
- BH3 domain binding [ISO, ISS]
- channel activity [IBA, ISO, ISS]
- chaperone binding [IPI]
- heat shock protein binding [IPI]
- identical protein binding [ISO]
- lipid binding [ISO, ISS]
- protein binding [IPI]
- protein complex binding [IPI]
- protein heterodimerization activity [IPI, ISO]
- protein homodimerization activity [IBA, ISO]
Gene Ontology Cellular Component
- BAX complex [ISO, ISS]
- Bcl-2 family protein complex [ISO, ISS]
- cell [ISO]
- cytoplasm [IDA, ISO]
- cytosol [IDA, ISO]
- endoplasmic reticulum [ISO]
- endoplasmic reticulum membrane [ISO, ISS]
- extracellular vesicular exosome [ISO]
- intracellular [ISO]
- membrane [ISO]
- mitochondrial membrane [IDA, ISO]
- mitochondrial outer membrane [IDA, ISO]
- mitochondrial permeability transition pore complex [ISO, ISS]
- mitochondrion [IDA, ISO]
- nuclear envelope [ISO]
- nucleus [ISO, ISS]
- pore complex [ISO, ISS]
Download Curated Data for this Protein
246997
10116
Switch View:
- Interactors 3
- Interactions 4
- Network