Rattus norvegicus
INSR
insulin receptor
GO Process (54)
GO Function (20)
GO Component (12)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [ISO]
- activation of MAPK activity [ISO]
- activation of protein kinase B activity [ISO]
- activation of protein kinase activity [ISO]
- cellular response to growth factor stimulus [ISO]
- cellular response to insulin stimulus [ISO]
- epidermis development [ISO]
- exocrine pancreas development [ISO]
- fat cell differentiation [IEP]
- glucose homeostasis [IDA, ISO]
- heart morphogenesis [ISO]
- insulin receptor signaling pathway [IDA, IMP, ISO]
- male sex determination [ISO]
- negative regulation of gene expression [IMP]
- negative regulation of protein phosphorylation [IMP]
- negative regulation of transporter activity [IMP]
- organ morphogenesis [ISO]
- peptidyl-tyrosine autophosphorylation [ISO]
- peptidyl-tyrosine phosphorylation [IMP, ISO]
- positive regulation of DNA replication [ISO]
- positive regulation of MAPK cascade [ISO]
- positive regulation of cell migration [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of developmental growth [ISO]
- positive regulation of glucose import [ISO]
- positive regulation of glycogen biosynthetic process [ISO]
- positive regulation of glycolytic process [ISO]
- positive regulation of glycoprotein biosynthetic process [IMP]
- positive regulation of mitosis [ISO]
- positive regulation of nitric oxide biosynthetic process [ISO]
- positive regulation of phosphorylation [IDA]
- positive regulation of protein kinase B signaling [ISO]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of respiratory burst [ISO]
- protein autophosphorylation [IDA, IMP, ISO]
- protein heterotetramerization [IDA, ISO]
- protein phosphorylation [IDA]
- regulation of embryonic development [ISO]
- regulation of hydrogen peroxide metabolic process [IDA]
- regulation of transcription, DNA-templated [ISO]
- response to activity [IEP]
- response to estradiol [IEP]
- response to ethanol [IEP]
- response to glucocorticoid [IEP]
- response to glucose [IEP]
- response to hormone [IEP]
- response to insulin [IEP]
- response to manganese ion [IEP]
- response to nutrient levels [IEP]
- response to testosterone [IEP]
- response to tumor necrosis factor [IMP]
- response to vitamin D [IEP]
- signal transduction by phosphorylation [ISO]
- transformation of host cell by virus [ISO]
Gene Ontology Molecular Function- 3-phosphoinositide-dependent protein kinase binding [IDA]
- ATP binding [ISO]
- GTP binding [ISO]
- PTB domain binding [ISO]
- insulin binding [IDA, IMP, ISO]
- insulin receptor substrate binding [IMP, ISO]
- insulin-activated receptor activity [IDA, IMP, ISO]
- insulin-like growth factor I binding [ISO]
- insulin-like growth factor II binding [ISO]
- insulin-like growth factor receptor binding [ISO]
- lipoic acid binding [IPI]
- phosphatidylinositol 3-kinase binding [ISO]
- protein binding [IPI]
- protein complex binding [IDA]
- protein domain specific binding [IPI]
- protein kinase activity [IDA]
- protein kinase binding [IPI]
- protein phosphatase binding [IMP]
- protein tyrosine kinase activity [IDA, ISO]
- receptor signaling protein tyrosine kinase activity [ISO]
- 3-phosphoinositide-dependent protein kinase binding [IDA]
- ATP binding [ISO]
- GTP binding [ISO]
- PTB domain binding [ISO]
- insulin binding [IDA, IMP, ISO]
- insulin receptor substrate binding [IMP, ISO]
- insulin-activated receptor activity [IDA, IMP, ISO]
- insulin-like growth factor I binding [ISO]
- insulin-like growth factor II binding [ISO]
- insulin-like growth factor receptor binding [ISO]
- lipoic acid binding [IPI]
- phosphatidylinositol 3-kinase binding [ISO]
- protein binding [IPI]
- protein complex binding [IDA]
- protein domain specific binding [IPI]
- protein kinase activity [IDA]
- protein kinase binding [IPI]
- protein phosphatase binding [IMP]
- protein tyrosine kinase activity [IDA, ISO]
- receptor signaling protein tyrosine kinase activity [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
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- Interactors 10
- Interactions 17
- Network