Rattus norvegicus
PTK2
FAK, FRNK, p125FAK
protein tyrosine kinase 2
GO Process (58)
GO Function (11)
GO Component (14)
Gene Ontology Biological Process
- JNK cascade [IMP]
- MAPK cascade [IMP]
- angiogenesis [IBA, ISO]
- blood vessel development [ISO]
- cellular chloride ion homeostasis [IMP]
- cellular response to transforming growth factor beta stimulus [ISO]
- central nervous system neuron axonogenesis [ISO]
- cytoskeleton organization [IBA]
- endothelial cell migration [ISO]
- ephrin receptor signaling pathway [ISO, ISS]
- epidermal growth factor receptor signaling pathway [IBA]
- establishment of nucleus localization [ISO]
- extracellular matrix organization [ISO]
- fat cell differentiation [IEP]
- growth hormone receptor signaling pathway [ISO]
- innate immune response [IBA]
- integrin-mediated signaling pathway [ISO, ISS]
- microtubule cytoskeleton organization [ISO]
- negative regulation of anoikis [ISO]
- negative regulation of apoptotic process [IMP, ISO]
- negative regulation of axonogenesis [ISO]
- negative regulation of cell migration [IMP]
- negative regulation of cell-cell adhesion [ISO]
- negative regulation of organ growth [ISO]
- negative regulation of synapse assembly [ISO]
- neuron migration [ISO]
- peptidyl-tyrosine autophosphorylation [IBA]
- peptidyl-tyrosine phosphorylation [ISO, ISS]
- positive regulation of cell adhesion [IMP]
- positive regulation of cell growth [IMP]
- positive regulation of cell migration [IMP, ISO]
- positive regulation of cell proliferation [ISO, ISS]
- positive regulation of glial cell proliferation [IMP]
- positive regulation of phagocytosis [IMP]
- positive regulation of phosphatidylinositol 3-kinase signaling [ISO, ISS]
- positive regulation of protein kinase B signaling [ISO, ISS]
- positive regulation of protein kinase activity [ISO, ISS]
- positive regulation of protein phosphorylation [ISO, ISS]
- positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [ISO, ISS]
- positive regulation of smooth muscle cell migration [IMP]
- positive regulation of smooth muscle cell proliferation [IMP]
- positive regulation of synaptic transmission [IMP]
- positive regulation of vasodilation [IMP]
- protein autophosphorylation [ISO, ISS]
- regulation of cell adhesion mediated by integrin [ISO, ISS]
- regulation of cell proliferation [ISO, ISS]
- regulation of cell shape [ISO, ISS]
- regulation of osteoblast differentiation [ISO, ISS]
- response to arsenic-containing substance [IEP]
- response to drug [IEP]
- response to estradiol [IEP]
- response to glucose [IEP]
- response to mechanical stimulus [IEP]
- response to organic cyclic compound [IEP]
- response to organic substance [IEP]
- response to organonitrogen compound [IEP]
- transforming growth factor beta receptor signaling pathway [ISO]
- vasculogenesis [ISO]
Gene Ontology Molecular Function- JUN kinase binding [ISO]
- SH2 domain binding [ISO]
- actin binding [ISO]
- identical protein binding [IPI]
- integrin binding [IPI]
- non-membrane spanning protein tyrosine kinase activity [IBA, ISO, ISS]
- phosphatidylinositol 3-kinase binding [IPI]
- protein binding [IPI]
- protein complex binding [IPI]
- protein kinase binding [ISO]
- protein tyrosine kinase activity [ISO, TAS]
- JUN kinase binding [ISO]
- SH2 domain binding [ISO]
- actin binding [ISO]
- identical protein binding [IPI]
- integrin binding [IPI]
- non-membrane spanning protein tyrosine kinase activity [IBA, ISO, ISS]
- phosphatidylinositol 3-kinase binding [IPI]
- protein binding [IPI]
- protein complex binding [IPI]
- protein kinase binding [ISO]
- protein tyrosine kinase activity [ISO, TAS]
Gene Ontology Cellular Component
- apical plasma membrane [IDA, ISO]
- basolateral plasma membrane [IDA]
- cytoplasm [ISO]
- cytosol [ISO, ISS]
- extrinsic component of cytoplasmic side of plasma membrane [IBA]
- focal adhesion [IDA, ISO, TAS]
- intercalated disc [IDA]
- lamellipodium [ISO]
- nuclear body [IDA]
- nucleolus [IDA]
- nucleus [IDA, ISO]
- plasma membrane [ISO]
- sarcolemma [IDA]
- stress fiber [ISO]
Download Curated Data for this Protein
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10116
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- Interactors 7
- Interactions 7
- Network