Rattus norvegicus
PTPN11
Shp2
protein tyrosine phosphatase, non-receptor type 11
GO Process (41)
GO Function (12)
GO Component (5)
Gene Ontology Biological Process
- DNA damage checkpoint [ISO]
- ERBB signaling pathway [ISO]
- abortive mitotic cell cycle [ISO]
- activation of MAPK activity [ISO]
- atrioventricular canal development [ISO]
- axonogenesis [ISO]
- brain development [ISO]
- dephosphorylation [ISO]
- ephrin receptor signaling pathway [ISO, ISS]
- epidermal growth factor receptor signaling pathway [ISO]
- face morphogenesis [ISO]
- genitalia development [ISO]
- glucose homeostasis [ISO]
- heart development [ISO]
- hormone metabolic process [ISO]
- hormone-mediated signaling pathway [ISO]
- inner ear development [ISO]
- integrin-mediated signaling pathway [ISO]
- lipid metabolic process [ISO]
- megakaryocyte development [ISO]
- multicellular organismal reproductive process [ISO]
- negative regulation of cell adhesion mediated by integrin [ISO]
- negative regulation of cortisol secretion [ISO]
- negative regulation of growth hormone secretion [ISO]
- negative regulation of hormone secretion [ISO]
- negative regulation of insulin secretion [ISO]
- neurotrophin TRK receptor signaling pathway [ISO]
- organ growth [ISO]
- peptidyl-tyrosine dephosphorylation [ISO, ISS]
- platelet formation [ISO]
- platelet-derived growth factor receptor signaling pathway [ISO]
- positive regulation of ERK1 and ERK2 cascade [ISO]
- positive regulation of glucose import in response to insulin stimulus [ISO]
- positive regulation of hormone secretion [ISO]
- positive regulation of mitotic cell cycle [ISO]
- positive regulation of signal transduction [ISO]
- protein dephosphorylation [IDA]
- regulation of cell adhesion mediated by integrin [ISO, ISS]
- regulation of multicellular organism growth [ISO]
- regulation of protein export from nucleus [ISO]
- triglyceride metabolic process [ISO]
Gene Ontology Molecular Function- D1 dopamine receptor binding [IPI]
- SH3/SH2 adaptor activity [ISO]
- insulin receptor binding [IDA, ISO]
- insulin receptor substrate binding [IPI]
- non-membrane spanning protein tyrosine phosphatase activity [ISO, ISS]
- peptide hormone receptor binding [ISO]
- phospholipase binding [IDA]
- phosphoprotein phosphatase activity [ISO]
- protein binding [IPI]
- protein domain specific binding [IPI]
- protein tyrosine phosphatase activity [IDA, ISO]
- receptor tyrosine kinase binding [ISO]
- D1 dopamine receptor binding [IPI]
- SH3/SH2 adaptor activity [ISO]
- insulin receptor binding [IDA, ISO]
- insulin receptor substrate binding [IPI]
- non-membrane spanning protein tyrosine phosphatase activity [ISO, ISS]
- peptide hormone receptor binding [ISO]
- phospholipase binding [IDA]
- phosphoprotein phosphatase activity [ISO]
- protein binding [IPI]
- protein domain specific binding [IPI]
- protein tyrosine phosphatase activity [IDA, ISO]
- receptor tyrosine kinase binding [ISO]
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- Interactors 6
- Interactions 9
- Network