Rattus norvegicus
PTGS2
COX-2, Cox2
prostaglandin-endoperoxide synthase 2
GO Process (57)
GO Function (7)
GO Component (5)
Gene Ontology Biological Process
- angiogenesis [IMP]
- bone mineralization [IMP]
- brown fat cell differentiation [ISO]
- cellular response to ATP [IEP]
- cellular response to UV [IEP]
- cellular response to hypoxia [ISO]
- cellular response to mechanical stimulus [IEP]
- cyclooxygenase pathway [ISO, ISS]
- decidualization [IMP, ISO]
- embryo implantation [IMP, ISO]
- hair cycle [IEP]
- inflammatory response [IMP]
- learning [IMP]
- maintenance of blood-brain barrier [IMP]
- memory [IMP]
- negative regulation of calcium ion transport [IMP]
- negative regulation of cell cycle [IGI]
- negative regulation of cell proliferation [IDA]
- negative regulation of smooth muscle contraction [IMP]
- negative regulation of synaptic transmission, dopaminergic [IMP]
- ovulation [IMP]
- positive regulation of NF-kappaB import into nucleus [IMP]
- positive regulation of apoptotic process [IMP]
- positive regulation of brown fat cell differentiation [ISO]
- positive regulation of cell death [IMP]
- positive regulation of cell migration involved in sprouting angiogenesis [IMP]
- positive regulation of cell proliferation [IMP]
- positive regulation of fever generation [IDA, ISO]
- positive regulation of fibroblast growth factor production [IMP]
- positive regulation of nitric oxide biosynthetic process [IMP]
- positive regulation of platelet-derived growth factor production [IMP]
- positive regulation of smooth muscle cell proliferation [IMP]
- positive regulation of smooth muscle contraction [IMP]
- positive regulation of synaptic plasticity [IMP]
- positive regulation of synaptic transmission, glutamatergic [IMP]
- positive regulation of transforming growth factor beta production [IMP]
- positive regulation of vasoconstriction [IMP]
- positive regulation vascular endothelial growth factor production [IMP]
- prostaglandin biosynthetic process [IMP, ISO]
- regulation of blood pressure [ISO, ISS]
- regulation of cell proliferation [ISO]
- response to cytokine [IMP]
- response to drug [IEP]
- response to estradiol [IEP]
- response to fatty acid [IEP]
- response to fructose [IEP]
- response to glucocorticoid [IEP]
- response to lipopolysaccharide [IMP]
- response to lithium ion [IEP]
- response to manganese ion [IEP]
- response to organic cyclic compound [IEP]
- response to organic substance [IEP]
- response to organonitrogen compound [IEP]
- response to radiation [IEP]
- response to tumor necrosis factor [IEP]
- response to vitamin D [IEP]
- sensory perception of pain [IMP]
Gene Ontology Molecular Function- enzyme binding [ISO]
- heme binding [ISO, ISS]
- lipid binding [IMP]
- oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [IDA]
- prostaglandin-endoperoxide synthase activity [ISO, ISS]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- enzyme binding [ISO]
- heme binding [ISO, ISS]
- lipid binding [IMP]
- oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [IDA]
- prostaglandin-endoperoxide synthase activity [ISO, ISS]
- protein binding [IPI]
- protein homodimerization activity [ISO]
Download Curated Data for this Protein
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- Interactors 6
- Interactions 7
- Network