Rattus norvegicus
P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
GO Process (78)
GO Function (13)
GO Component (17)
Gene Ontology Biological Process
- NAD transport [ISO]
- T cell homeostasis [ISO]
- T cell proliferation [ISO]
- activation of MAPK activity [ISO]
- apoptotic signaling pathway [IDA]
- bleb assembly [IDA, ISO]
- calcium ion transport [ISO]
- cation transmembrane transport [IDA, ISO, TAS]
- cation transport [ISO]
- cell morphogenesis [ISO]
- cell surface receptor signaling pathway [IDA]
- cell volume homeostasis [ISO]
- cellular response to extracellular stimulus [ISO]
- ceramide biosynthetic process [ISO]
- collagen metabolic process [ISO]
- cytolysis [ISO]
- defense response to Gram-positive bacterium [ISO]
- extrinsic apoptotic signaling pathway [ISO]
- gene expression [ISO]
- homeostasis of number of cells within a tissue [ISO]
- inflammatory response [ISO]
- membrane budding [ISO]
- membrane depolarization [IDA, ISO]
- membrane protein ectodomain proteolysis [ISO]
- mitochondrion organization [ISO]
- multicellular organismal protein catabolic process [ISO]
- negative regulation of MAPK cascade [ISO]
- negative regulation of bone resorption [ISO]
- neuronal action potential [IDA]
- organic cation transport [TAS]
- phagolysosome assembly [ISO]
- phospholipid transfer to membrane [ISO]
- phospholipid translocation [ISO]
- plasma membrane organization [ISO]
- pore complex assembly [IDA, IMP, ISO]
- positive regulation of MAPK cascade [ISO]
- positive regulation of T cell mediated cytotoxicity [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of bone mineralization [ISO]
- positive regulation of calcium ion transport into cytosol [ISO]
- positive regulation of catalytic activity [ISO]
- positive regulation of cytokine secretion [ISO]
- positive regulation of cytolysis [IDA]
- positive regulation of cytoskeleton organization [IDA]
- positive regulation of gamma-aminobutyric acid secretion [ISO]
- positive regulation of glutamate secretion [ISO]
- positive regulation of interleukin-1 alpha secretion [ISO]
- positive regulation of interleukin-1 beta production [ISO]
- positive regulation of interleukin-1 beta secretion [IDA, IMP, ISO]
- positive regulation of interleukin-6 production [ISO]
- positive regulation of lymphocyte apoptotic process [ISO]
- positive regulation of mitochondrial depolarization [ISO]
- positive regulation of ossification [ISO]
- positive regulation of prostaglandin secretion [ISO]
- positive regulation of protein phosphorylation [IDA, ISO]
- positive regulation of protein secretion [ISO]
- programmed cell death [ISO]
- protein oligomerization [ISO]
- protein phosphorylation [ISO]
- protein processing [ISO]
- purinergic nucleotide receptor signaling pathway [IDA, ISO]
- reactive oxygen species metabolic process [ISO]
- regulation of sodium ion transport [IDA]
- release of sequestered calcium ion into cytosol [ISO]
- response to ATP [IDA, ISO]
- response to bacterium [ISO]
- response to calcium ion [ISO]
- response to drug [ISO]
- response to electrical stimulus [ISO]
- response to fluid shear stress [ISO]
- response to lipopolysaccharide [ISO]
- response to mechanical stimulus [ISO]
- response to organic cyclic compound [ISO]
- response to organic substance [ISO]
- response to zinc ion [ISO]
- sensory perception of pain [ISO]
- skeletal system morphogenesis [ISO]
- synaptic vesicle exocytosis [ISO]
Gene Ontology Molecular Function- ATP binding [IDA, ISO]
- channel activity [IDA, ISO]
- copper ion binding [IDA]
- extracellular ATP-gated cation channel activity [IDA, ISO, TAS]
- lipopolysaccharide binding [ISO]
- magnesium ion binding [IDA]
- protein binding [IPI]
- protein serine/threonine kinase activator activity [IC, IMP]
- purinergic nucleotide receptor activity [IDA, ISO]
- receptor activity [ISO]
- receptor binding [IPI]
- scaffold protein binding [IPI]
- zinc ion binding [IDA]
- ATP binding [IDA, ISO]
- channel activity [IDA, ISO]
- copper ion binding [IDA]
- extracellular ATP-gated cation channel activity [IDA, ISO, TAS]
- lipopolysaccharide binding [ISO]
- magnesium ion binding [IDA]
- protein binding [IPI]
- protein serine/threonine kinase activator activity [IC, IMP]
- purinergic nucleotide receptor activity [IDA, ISO]
- receptor activity [ISO]
- receptor binding [IPI]
- scaffold protein binding [IPI]
- zinc ion binding [IDA]
Gene Ontology Cellular Component
- bleb [IDA]
- cell-cell junction [ISO]
- cytoplasm [IDA]
- cytosol [ISO]
- external side of plasma membrane [ISO]
- integral component of nuclear inner membrane [IDA]
- integral component of plasma membrane [ISO]
- intracellular [ISO]
- membrane [ISO]
- membrane raft [IDA]
- neuromuscular junction [ISO]
- neuron projection [IDA]
- neuronal cell body [ISO]
- plasma membrane [IDA, ISO, TAS]
- protein complex [IDA]
- synapse [ISO]
- terminal bouton [IDA]
Download Curated Data for this Protein
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- Interactors 11
- Interactions 22
- Network