Rattus norvegicus
PTEN
MMAC1, Mmac, TEP1
phosphatase and tensin homolog
GO Process (84)
GO Function (14)
GO Component (13)
Gene Ontology Biological Process
- activation of mitotic anaphase-promoting complex activity [ISO]
- aging [IEP]
- angiogenesis [ISO]
- brain morphogenesis [ISO]
- canonical Wnt signaling pathway [ISO]
- cardiac muscle tissue development [ISO]
- cell migration [ISO]
- central nervous system development [ISO]
- central nervous system myelin maintenance [ISO]
- central nervous system neuron axonogenesis [ISO]
- dendritic spine morphogenesis [ISO]
- dentate gyrus development [ISO]
- dephosphorylation [ISO]
- endothelial cell migration [ISO]
- forebrain morphogenesis [ISO]
- heart development [ISO]
- inositol phosphate dephosphorylation [ISO]
- learning or memory [ISO]
- locomotor rhythm [ISO]
- locomotory behavior [ISO]
- long term synaptic depression [IMP]
- long-term synaptic potentiation [ISO]
- male mating behavior [ISO]
- maternal behavior [ISO]
- memory [IMP]
- multicellular organismal response to stress [ISO]
- negative regulation of G1/S transition of mitotic cell cycle [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of axonogenesis [ISO]
- negative regulation of cell aging [ISO]
- negative regulation of cell migration [ISO]
- negative regulation of cell proliferation [IDA, ISO]
- negative regulation of cell size [ISO]
- negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [ISO]
- negative regulation of dendritic spine morphogenesis [ISO]
- negative regulation of epithelial cell proliferation [ISO]
- negative regulation of excitatory postsynaptic membrane potential [ISO]
- negative regulation of focal adhesion assembly [ISO]
- negative regulation of myelination [ISO]
- negative regulation of organ growth [ISO]
- negative regulation of phagocytosis [IMP]
- negative regulation of protein kinase B signaling [ISO]
- negative regulation of protein phosphorylation [ISO]
- negative regulation of ribosome biogenesis [ISO]
- negative regulation of synaptic vesicle clustering [ISO]
- neuron projection development [IDA]
- neuron-neuron synaptic transmission [ISO]
- peptidyl-tyrosine dephosphorylation [ISO]
- phosphatidylinositol dephosphorylation [IMP, ISO]
- platelet-derived growth factor receptor signaling pathway [IDA]
- positive regulation of apoptotic process [IMP]
- positive regulation of apoptotic signaling pathway [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of excitatory postsynaptic membrane potential [ISO]
- positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [ISO]
- positive regulation of sequence-specific DNA binding transcription factor activity [ISO]
- postsynaptic density assembly [ISO]
- prepulse inhibition [ISO]
- presynaptic membrane assembly [ISO]
- prostate gland growth [ISO]
- protein dephosphorylation [ISO]
- protein kinase B signaling [ISO]
- protein stabilization [ISO]
- regulation of B cell apoptotic process [ISO]
- regulation of cell cycle [ISO]
- regulation of cellular component size [ISO]
- regulation of myeloid cell apoptotic process [ISO]
- regulation of neuron projection development [ISO]
- regulation of protein stability [ISO]
- response to ATP [IEP]
- response to arsenic-containing substance [IEP]
- response to drug [IEP]
- response to estradiol [IEP]
- response to ethanol [IEP]
- response to glucose [IEP]
- response to inorganic substance [IEP]
- response to nutrient [IEP]
- response to organic cyclic compound [IEP]
- response to organic substance [IEP]
- response to zinc ion [IEP]
- rhythmic synaptic transmission [ISO]
- social behavior [ISO]
- synapse assembly [ISO]
- synapse maturation [ISO]
Gene Ontology Molecular Function- PDZ domain binding [IPI, ISO]
- anaphase-promoting complex binding [ISO]
- enzyme binding [ISO]
- inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [ISO]
- phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [IDA, IMP, ISO]
- phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [ISO]
- phosphatidylinositol-3-phosphatase activity [ISO]
- phosphoprotein phosphatase activity [ISO]
- platelet-derived growth factor receptor binding [IDA]
- protein binding [IPI]
- protein kinase binding [ISO]
- protein serine/threonine phosphatase activity [ISO]
- protein tyrosine phosphatase activity [ISO]
- protein tyrosine/serine/threonine phosphatase activity [TAS]
- PDZ domain binding [IPI, ISO]
- anaphase-promoting complex binding [ISO]
- enzyme binding [ISO]
- inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [ISO]
- phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [IDA, IMP, ISO]
- phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [ISO]
- phosphatidylinositol-3-phosphatase activity [ISO]
- phosphoprotein phosphatase activity [ISO]
- platelet-derived growth factor receptor binding [IDA]
- protein binding [IPI]
- protein kinase binding [ISO]
- protein serine/threonine phosphatase activity [ISO]
- protein tyrosine phosphatase activity [ISO]
- protein tyrosine/serine/threonine phosphatase activity [TAS]
Gene Ontology Cellular Component
- Schmidt-Lanterman incisure [ISO]
- cell projection [ISO]
- cytoplasm [IDA, ISO]
- cytoplasmic side of plasma membrane [ISO]
- dendritic spine [IDA]
- intracellular [ISO]
- mitochondrion [IDA]
- myelin sheath adaxonal region [ISO]
- neuron projection [IDA, ISO]
- nucleoplasm [ISO]
- nucleus [IDA, ISO]
- plasma membrane [ISO]
- postsynaptic membrane [IDA]
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