Rattus norvegicus
EIF2AK2
Pkr, Prkr
eukaryotic translation initiation factor 2-alpha kinase 2
GO Process (27)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- activation of MAPKK activity [ISO, ISS]
- endoplasmic reticulum unfolded protein response [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of osteoblast proliferation [ISO, ISS]
- negative regulation of translation [ISO, ISS]
- negative regulation of viral genome replication [ISO, ISS]
- positive regulation of NF-kappaB transcription factor activity [ISO, ISS]
- positive regulation of NIK/NF-kappaB signaling [ISO, ISS]
- positive regulation of apoptotic process [IMP]
- positive regulation of chemokine production [ISO, ISS]
- positive regulation of cytokine production [ISO, ISS]
- positive regulation of stress-activated MAPK cascade [ISO, ISS]
- protein autophosphorylation [ISO, ISS]
- protein phosphorylation [ISO, ISS]
- regulation of NLRP3 inflammasome complex assembly [ISO, ISS]
- regulation of hematopoietic progenitor cell differentiation [ISO, ISS]
- regulation of hematopoietic stem cell differentiation [ISO, ISS]
- regulation of hematopoietic stem cell proliferation [ISO, ISS]
- response to exogenous dsRNA [IEP]
- response to interferon-alpha [ISO, ISS]
- response to lipopolysaccharide [IMP]
- response to mechanical stimulus [IEP]
- response to organic substance [IEP]
- response to toxic substance [IMP]
- response to virus [ISO, ISS]
- response to vitamin E [IPI]
- translation [ISO]
Gene Ontology Molecular Function
Download Curated Data for this Protein
248507
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- Interactors 3
- Interactions 3
- Network