Rattus norvegicus
TGFB1
Tgfb
transforming growth factor, beta 1
GO Process (152)
GO Function (9)
GO Component (11)
Gene Ontology Biological Process
- ATP biosynthetic process [ISO, ISS]
- MAPK cascade [ISO, ISS]
- SMAD protein complex assembly [ISO, ISS]
- SMAD protein import into nucleus [IDA, ISO]
- SMAD protein signal transduction [IBA]
- T cell activation [ISO]
- T cell differentiation [ISO]
- T cell homeostasis [ISO]
- adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [ISO]
- aging [IEP]
- branch elongation involved in mammary gland duct branching [ISO]
- cell activation [ISO]
- cell cycle arrest [ISO, ISS]
- cell proliferation [ISO]
- cell-cell junction organization [ISO, ISS]
- cellular calcium ion homeostasis [ISO]
- cellular response to dexamethasone stimulus [IDA]
- cellular response to growth factor stimulus [ISO]
- cellular response to organic cyclic compound [ISO, ISS]
- cellular response to transforming growth factor beta stimulus [ISO]
- chondrocyte differentiation [ISO, ISS]
- common-partner SMAD protein phosphorylation [ISO, ISS]
- defense response to fungus, incompatible interaction [IDA]
- digestive tract development [IEP]
- embryo development [IEP]
- endoderm development [ISO]
- epidermal growth factor receptor signaling pathway [ISO, ISS]
- epithelial to mesenchymal transition [IDA]
- evasion or tolerance of host defenses by virus [ISO, ISS]
- extracellular matrix assembly [ISO, ISS]
- extrinsic apoptotic signaling pathway [ISO, ISS]
- female pregnancy [IEP]
- frontal suture morphogenesis [IEP]
- germ cell migration [ISO]
- hematopoietic progenitor cell differentiation [ISO, ISS]
- hyaluronan catabolic process [ISO, ISS]
- inflammatory response [ISO]
- inner ear development [IEP]
- lens fiber cell differentiation [ISO]
- lipopolysaccharide-mediated signaling pathway [ISO, ISS]
- lung development [TAS]
- lymph node development [ISO]
- mammary gland branching involved in thelarche [ISO]
- mammary gland development [ISO]
- mitotic cell cycle checkpoint [ISO, ISS]
- mononuclear cell proliferation [ISO]
- morphogenesis of a branching structure [IDA]
- myelination [IMP]
- myeloid dendritic cell differentiation [ISO]
- negative regulation of DNA replication [ISO, ISS]
- negative regulation of T cell activation [ISO]
- negative regulation of T cell proliferation [ISO]
- negative regulation of blood vessel endothelial cell migration [ISO, ISS]
- negative regulation of cell cycle [ISO, ISS]
- negative regulation of cell growth [ISO, ISS]
- negative regulation of cell proliferation [ISO, ISS]
- negative regulation of cell-cell adhesion [ISO, ISS]
- negative regulation of epithelial cell proliferation [IDA, ISO]
- negative regulation of fat cell differentiation [ISO, ISS]
- negative regulation of gene expression [ISO]
- negative regulation of hyaluronan biosynthetic process [ISO, ISS]
- negative regulation of immune response [IDA]
- negative regulation of macrophage cytokine production [ISO]
- negative regulation of mitotic cell cycle [ISO, ISS]
- negative regulation of myoblast differentiation [ISO, ISS]
- negative regulation of neuroblast proliferation [IDA]
- negative regulation of ossification [ISO]
- negative regulation of phagocytosis [IDA]
- negative regulation of protein phosphorylation [ISO, ISS]
- negative regulation of release of sequestered calcium ion into cytosol [IDA]
- negative regulation of skeletal muscle tissue development [ISO, ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [ISO, ISS]
- organ regeneration [IMP]
- ossification involved in bone remodeling [ISO]
- pathway-restricted SMAD protein phosphorylation [ISO, ISS]
- phosphate-containing compound metabolic process [ISO, ISS]
- positive regulation of MAP kinase activity [ISO, ISS]
- positive regulation of NAD+ ADP-ribosyltransferase activity [ISO, ISS]
- positive regulation of NF-kappaB transcription factor activity [IDA]
- positive regulation of SMAD protein import into nucleus [ISO]
- positive regulation of apoptotic process [IDA, IMP]
- positive regulation of blood vessel endothelial cell migration [ISO, ISS]
- positive regulation of bone mineralization [ISO]
- positive regulation of branching involved in ureteric bud morphogenesis [IMP]
- positive regulation of cell cycle arrest [ISO]
- positive regulation of cell migration [ISO, ISS]
- positive regulation of cell proliferation [ISO, ISS]
- positive regulation of cellular protein metabolic process [ISO, ISS]
- positive regulation of chemotaxis [ISO, ISS]
- positive regulation of collagen biosynthetic process [ISO, ISS]
- positive regulation of epithelial cell proliferation [IDA]
- positive regulation of epithelial to mesenchymal transition [ISO, ISS]
- positive regulation of exit from mitosis [IDA]
- positive regulation of fibroblast migration [ISO, ISS]
- positive regulation of gene expression [ISO, ISS]
- positive regulation of histone acetylation [ISO]
- positive regulation of histone deacetylation [ISO]
- positive regulation of interleukin-17 production [ISO, ISS]
- positive regulation of isotype switching to IgA isotypes [ISO]
- positive regulation of odontogenesis [ISO]
- positive regulation of pathway-restricted SMAD protein phosphorylation [IBA, ISO, ISS]
- positive regulation of peptidyl-serine phosphorylation [ISO, ISS]
- positive regulation of peptidyl-threonine phosphorylation [ISO, ISS]
- positive regulation of phosphatidylinositol 3-kinase activity [ISO, ISS]
- positive regulation of protein complex assembly [ISO, ISS]
- positive regulation of protein dephosphorylation [ISO, ISS]
- positive regulation of protein import into nucleus [ISO]
- positive regulation of protein kinase B signaling [ISO, ISS]
- positive regulation of protein localization to nucleus [ISO]
- positive regulation of protein phosphorylation [ISO, ISS]
- positive regulation of protein secretion [ISO, ISS]
- positive regulation of smooth muscle cell differentiation [IDA]
- positive regulation of superoxide anion generation [ISO, ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription regulatory region DNA binding [ISO, ISS]
- positive regulation of transcription, DNA-templated [ISO, ISS]
- protein export from nucleus [ISO, ISS]
- protein import into nucleus, translocation [ISO, ISS]
- protein kinase B signaling [ISO, ISS]
- protein phosphorylation [ISO]
- receptor catabolic process [ISO, ISS]
- regulation of DNA binding [ISO]
- regulation of MAPK cascade [IBA]
- regulation of actin cytoskeleton reorganization [ISO]
- regulation of binding [ISO]
- regulation of branching involved in mammary gland duct morphogenesis [ISO]
- regulation of cartilage development [ISO]
- regulation of cell growth [TAS]
- regulation of cell proliferation [ISO, TAS]
- regulation of miRNA metabolic process [ISO]
- regulation of protein import into nucleus [ISO]
- regulation of sodium ion transport [ISO]
- regulation of striated muscle tissue development [ISO]
- regulation of transforming growth factor beta receptor signaling pathway [ISO, ISS]
- regulatory T cell differentiation [ISO]
- response to cholesterol [ISO, ISS]
- response to drug [IEP]
- response to estradiol [IEP, ISO]
- response to glucose [IEP]
- response to hypoxia [IEP]
- response to laminar fluid shear stress [IEP]
- response to organic cyclic compound [IEP]
- response to organic substance [IDA]
- response to progesterone [ISO, ISS]
- response to radiation [IEP]
- response to vitamin D [IEP]
- response to wounding [ISO]
- salivary gland morphogenesis [ISO]
- tolerance induction to self antigen [ISO]
- transforming growth factor beta receptor signaling pathway [IBA, ISO, ISS]
- wound healing [IEP, IMP]
Gene Ontology Molecular Function- antigen binding [ISO]
- cytokine activity [IBA]
- enzyme binding [ISO]
- glycoprotein binding [ISO]
- protein N-terminus binding [IMP]
- protein heterodimerization activity [IDA]
- protein homodimerization activity [IDA]
- transforming growth factor beta receptor binding [IC, ISO, TAS]
- type II transforming growth factor beta receptor binding [IBA, ISO, ISS]
- antigen binding [ISO]
- cytokine activity [IBA]
- enzyme binding [ISO]
- glycoprotein binding [ISO]
- protein N-terminus binding [IMP]
- protein heterodimerization activity [IDA]
- protein homodimerization activity [IDA]
- transforming growth factor beta receptor binding [IC, ISO, TAS]
- type II transforming growth factor beta receptor binding [IBA, ISO, ISS]
Gene Ontology Cellular Component
Download Curated Data for this Protein
248721
10116
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