Rattus norvegicus
SREBF1
ADD-1, ADD1, SREBP-1, SREBP-1c, Srebp1
sterol regulatory element binding transcription factor 1
GO Process (31)
GO Function (10)
GO Component (6)
Gene Ontology Biological Process
- aging [IEP]
- cellular response to fatty acid [IEP]
- cellular response to insulin stimulus [IEP]
- cellular response to starvation [IDA, ISO]
- cholesterol metabolic process [IMP]
- insulin receptor signaling pathway [ISO]
- lipid biosynthetic process [ISO, ISS, TAS]
- lung development [IEP]
- negative regulation of insulin secretion [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of cholesterol biosynthetic process [ISO]
- positive regulation of histone deacetylation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- positive regulation of transcription, DNA-templated [IMP, ISO]
- positive regulation of triglyceride biosynthetic process [ISO, ISS]
- regulation of fatty acid metabolic process [ISO]
- regulation of heart rate by chemical signal [ISO]
- regulation of insulin secretion [ISO]
- regulation of transcription, DNA-templated [ISO]
- response to cAMP [IEP]
- response to drug [IEP]
- response to fatty acid [IEP]
- response to food [IEP]
- response to glucagon [IEP]
- response to glucose [ISO]
- response to insulin [TAS]
- response to lipid [IEP]
- response to organic cyclic compound [IEP]
- response to peptide hormone [IEP]
- response to progesterone [IEP]
- response to retinoic acid [IEP]
Gene Ontology Molecular Function- DNA binding [ISO, ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin binding [IDA, ISO]
- protein complex binding [IPI]
- protein kinase binding [ISO]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [ISO, ISS]
- sterol response element binding [ISO, ISS]
- transcription regulatory region DNA binding [ISO]
- DNA binding [ISO, ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin binding [IDA, ISO]
- protein complex binding [IPI]
- protein kinase binding [ISO]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [ISO, ISS]
- sterol response element binding [ISO, ISS]
- transcription regulatory region DNA binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
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- Interactors 10
- Interactions 13
- Network