Rattus norvegicus
PDE2A
Pde2, Pde2a2
phosphodiesterase 2A, cGMP-stimulated
GO Process (22)
GO Function (9)
GO Component (13)
Gene Ontology Biological Process
- cAMP catabolic process [IDA, ISO]
- cAMP-mediated signaling [IMP, ISO]
- cGMP catabolic process [IDA, ISO]
- cGMP-mediated signaling [ISO, ISS]
- cellular response to cGMP [ISO, ISS]
- cellular response to drug [ISO, ISS]
- cellular response to granulocyte macrophage colony-stimulating factor stimulus [ISO, ISS]
- cellular response to macrophage colony-stimulating factor stimulus [ISO, ISS]
- cellular response to mechanical stimulus [ISO, ISS]
- cellular response to transforming growth factor beta stimulus [ISO]
- establishment of endothelial barrier [IDA]
- metabolic process [ISO]
- monocyte differentiation [ISO]
- negative regulation of cAMP biosynthetic process [IMP, ISO]
- negative regulation of protein import into nucleus, translocation [ISO, ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISO, ISS]
- negative regulation of vascular permeability [ISO, ISS]
- positive regulation of gene expression [ISO]
- positive regulation of inflammatory response [ISO, ISS]
- positive regulation of vascular permeability [ISO, ISS]
- protein targeting to mitochondrion [IMP]
- regulation of cGMP metabolic process [ISO]
Gene Ontology Molecular Function- GAF domain binding [ISO]
- TPR domain binding [ISO]
- cAMP binding [IDA, ISO]
- cGMP binding [IDA, ISO]
- cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [IDA, ISO]
- cyclic-nucleotide phosphodiesterase activity [ISO, ISS]
- drug binding [ISO, ISS]
- protein binding [IPI]
- protein homodimerization activity [IDA, ISO]
- GAF domain binding [ISO]
- TPR domain binding [ISO]
- cAMP binding [IDA, ISO]
- cGMP binding [IDA, ISO]
- cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [IDA, ISO]
- cyclic-nucleotide phosphodiesterase activity [ISO, ISS]
- drug binding [ISO, ISS]
- protein binding [IPI]
- protein homodimerization activity [IDA, ISO]
Gene Ontology Cellular Component
- Golgi apparatus [ISO, ISS]
- axon [ISO]
- cytoplasm [IDA, ISO]
- cytosol [ISO, ISS]
- dendrite [ISO]
- endoplasmic reticulum [ISO, ISS]
- intracellular [ISO]
- membrane raft [IDA]
- mitochondrial matrix [IDA]
- nucleus [ISO, ISS]
- perinuclear region of cytoplasm [ISO, ISS]
- plasma membrane [ISO, ISS]
- presynaptic membrane [ISO, ISS]
Download Curated Data for this Protein
249615
10116
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- Interactors 4
- Interactions 4
- Network