Rattus norvegicus
MAP3K1
Mekk1
mitogen activated protein kinase kinase kinase 1
GO Process (27)
GO Function (11)
GO Component (4)
Gene Ontology Biological Process
- JNK cascade [ISO]
- MAPK cascade [IDA]
- activation of JNKK activity [IDA]
- activation of JUN kinase activity [ISO]
- activation of MAPKK activity [IDA]
- apoptotic mitochondrial changes [ISO]
- camera-type eye development [ISO]
- cellular response to mechanical stimulus [ISO]
- epithelial cell morphogenesis [ISO]
- eyelid development in camera-type eye [ISO]
- negative regulation of actin filament bundle assembly [IDA]
- peptidyl-serine phosphorylation [IDA]
- positive regulation of JUN kinase activity [IDA]
- positive regulation of MAP kinase activity [IDA]
- positive regulation of actin filament polymerization [ISO]
- positive regulation of apoptotic process [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of viral transcription [IDA]
- protein autophosphorylation [IDA, IMP]
- protein oligomerization [IDA]
- protein phosphorylation [IDA]
- protein polyubiquitination [IMP]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IGI]
- regulation of cell migration [ISO]
- response to osmotic stress [IMP]
- transforming growth factor beta receptor signaling pathway [ISO]
- wound healing [ISO]
Gene Ontology Molecular Function- JUN kinase binding [IPI]
- JUN kinase kinase activity [ISO]
- JUN kinase kinase kinase activity [IDA]
- MAP kinase kinase kinase activity [IDA]
- mitogen-activated protein kinase binding [IPI]
- mitogen-activated protein kinase kinase binding [IPI]
- protein binding [IPI]
- protein kinase activity [ISO]
- protein kinase binding [ISO]
- sphingolipid binding [IPI]
- ubiquitin-protein transferase activity [IMP]
- JUN kinase binding [IPI]
- JUN kinase kinase activity [ISO]
- JUN kinase kinase kinase activity [IDA]
- MAP kinase kinase kinase activity [IDA]
- mitogen-activated protein kinase binding [IPI]
- mitogen-activated protein kinase kinase binding [IPI]
- protein binding [IPI]
- protein kinase activity [ISO]
- protein kinase binding [ISO]
- sphingolipid binding [IPI]
- ubiquitin-protein transferase activity [IMP]
Gene Ontology Cellular Component
Download Curated Data for this Protein
250551
10116
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- Interactors 1
- Interactions 1
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