Rattus norvegicus
RAPGEF2
PDZ-GEF1, RA-GEF-1, nRap GEP
Rap guanine nucleotide exchange factor (GEF) 2
GO Process (32)
GO Function (10)
GO Component (11)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [ISO, ISS]
- Rap protein signal transduction [ISO, ISS]
- adenylate cyclase-activating adrenergic receptor signaling pathway [ISO, ISS]
- blood vessel development [ISO, ISS]
- brain-derived neurotrophic factor receptor signaling pathway [IMP]
- cAMP-mediated signaling [ISO, ISS]
- cellular response to cAMP [ISO, ISS]
- cellular response to cGMP [ISO, ISS]
- cellular response to nerve growth factor stimulus [IDA]
- establishment of endothelial barrier [ISO, ISS]
- forebrain neuron development [ISO, ISS]
- negative regulation of cell proliferation [ISO, ISS]
- negative regulation of dendrite morphogenesis [ISO, ISS]
- negative regulation of melanin biosynthetic process [ISO, ISS]
- nerve growth factor signaling pathway [IDA]
- neuron migration [ISO, ISS]
- neuron projection development [ISO, ISS]
- neuropeptide signaling pathway [ISO, ISS]
- positive regulation of ERK1 and ERK2 cascade [IMP, ISO, ISS]
- positive regulation of Rap GTPase activity [IDA, IMP, ISO]
- positive regulation of Ras GTPase activity [ISO, ISS]
- positive regulation of cAMP-dependent protein kinase activity [ISO, ISS]
- positive regulation of cAMP-mediated signaling [ISO, ISS]
- positive regulation of dendritic cell apoptotic process [ISO, ISS]
- positive regulation of neuron migration [ISO, ISS]
- positive regulation of neuron projection development [IMP]
- positive regulation of protein binding [ISO, ISS]
- positive regulation of protein kinase activity [IMP, ISO, ISS]
- positive regulation of vasculogenesis [ISO, ISS]
- regulation of cell junction assembly [ISO, ISS]
- regulation of synaptic plasticity [IDA]
- ventricular system development [ISO, ISS]
Gene Ontology Molecular Function- PDZ domain binding [ISO, ISS]
- Rap GTPase activator activity [ISO]
- Rap guanyl-nucleotide exchange factor activity [IMP, ISO, ISS]
- Ras guanyl-nucleotide exchange factor activity [ISO, ISS]
- WW domain binding [ISO, ISS]
- beta-1 adrenergic receptor binding [ISO, ISS]
- cAMP binding [ISO, ISS]
- cGMP binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- PDZ domain binding [ISO, ISS]
- Rap GTPase activator activity [ISO]
- Rap guanyl-nucleotide exchange factor activity [IMP, ISO, ISS]
- Ras guanyl-nucleotide exchange factor activity [ISO, ISS]
- WW domain binding [ISO, ISS]
- beta-1 adrenergic receptor binding [ISO, ISS]
- cAMP binding [ISO, ISS]
- cGMP binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
Gene Ontology Cellular Component
Download Curated Data for this Protein
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- Interactors 3
- Interactions 3
- Network