Rattus norvegicus
MDM2
MDM2 proto-oncogene, E3 ubiquitin protein ligase
GO Process (45)
GO Function (9)
GO Component (9)
Gene Ontology Biological Process
- DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [ISO]
- cellular response to UV-C [IEP]
- cellular response to alkaloid [IEP]
- cellular response to antibiotic [IEP]
- cellular response to estrogen stimulus [IEP]
- cellular response to growth factor stimulus [IEP]
- cellular response to hydrogen peroxide [IEP]
- cellular response to hypoxia [ISO]
- cellular response to organic cyclic compound [IEP]
- cellular response to organic substance [IEP]
- cellular response to peptide hormone stimulus [IEP]
- cellular response to vitamin B1 [IEP]
- establishment of protein localization [ISO]
- negative regulation of DNA damage response, signal transduction by p53 class mediator [ISO]
- negative regulation of apoptotic process [IMP]
- negative regulation of cell cycle arrest [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- negative regulation of gene expression [IMP]
- negative regulation of protein processing [IMP]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [IDA, ISO]
- peptidyl-lysine modification [ISO]
- positive regulation of cell cycle [ISO]
- positive regulation of gene expression [IMP]
- positive regulation of mitotic cell cycle [ISO]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [ISO]
- positive regulation of protein export from nucleus [IMP]
- protein catabolic process [ISO]
- protein complex assembly [ISO]
- protein destabilization [ISO]
- protein localization to nucleus [ISO]
- protein ubiquitination [IMP, ISO]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [ISO]
- regulation of protein catabolic process [ISO]
- response to antibiotic [ISO]
- response to carbohydrate [IEP]
- response to cocaine [IEP]
- response to drug [IEP]
- response to ether [IEP]
- response to iron ion [IEP]
- response to magnesium ion [IEP]
- response to morphine [IEP]
- response to steroid hormone [IEP]
- response to toxic substance [IEP]
- traversing start control point of mitotic cell cycle [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
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- Interactors 17
- Interactions 35
- Network