Rattus norvegicus
SIRT2
sirtuin 2
GO Process (48)
GO Function (14)
GO Component (23)
Gene Ontology Biological Process
- cellular lipid catabolic process [ISO, ISS]
- cellular response to caloric restriction [ISO, ISS]
- cellular response to epinephrine stimulus [ISO, ISS]
- cellular response to hepatocyte growth factor stimulus [ISO, ISS]
- cellular response to hypoxia [ISO, ISS]
- cellular response to molecule of bacterial origin [ISO, ISS]
- cellular response to oxidative stress [ISO, ISS]
- central nervous system development [IEP]
- hepatocyte growth factor receptor signaling pathway [ISO, ISS]
- histone H3 deacetylation [ISO, ISS]
- histone H4 deacetylation [ISO, ISS]
- histone deacetylation [ISO]
- myelination in peripheral nervous system [IMP, ISO]
- negative regulation of NLRP3 inflammasome complex assembly [ISO]
- negative regulation of apoptotic process [IMP]
- negative regulation of autophagy [ISO, ISS]
- negative regulation of cell proliferation [ISO, ISS]
- negative regulation of defense response to bacterium [ISO, ISS]
- negative regulation of fat cell differentiation [ISO, ISS]
- negative regulation of oligodendrocyte differentiation [IMP]
- negative regulation of oligodendrocyte progenitor proliferation [IMP]
- negative regulation of peptidyl-threonine phosphorylation [ISO, ISS]
- negative regulation of protein catabolic process [ISO, ISS]
- negative regulation of reactive oxygen species metabolic process [ISO, ISS]
- negative regulation of striated muscle tissue development [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO, ISS]
- negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [ISO, ISS]
- negative regulation of transcription, DNA-templated [ISO]
- peptidyl-lysine deacetylation [ISO, ISS]
- phosphatidylinositol 3-kinase signaling [ISO, ISS]
- positive regulation of DNA binding [ISO, ISS]
- positive regulation of attachment of spindle microtubules to kinetochore [ISO, ISS]
- positive regulation of cell division [ISO, ISS]
- positive regulation of execution phase of apoptosis [ISO, ISS]
- positive regulation of meiosis [ISO, ISS]
- positive regulation of oocyte maturation [ISO, ISS]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [ISO, ISS]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [ISO, ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISO, ISS]
- proteasome-mediated ubiquitin-dependent protein catabolic process [ISO, ISS]
- protein deacetylation [IMP, ISO, ISS]
- protein kinase B signaling [ISO, ISS]
- regulation of cell cycle [ISO, ISS]
- regulation of fat cell differentiation [ISO]
- regulation of myelination [IMP, ISO]
- ripoptosome assembly involved in necroptotic process [ISO]
- substantia nigra development [ISO]
- tubulin deacetylation [IDA, ISO]
Gene Ontology Molecular Function
- NAD+ binding [ISO]
- NAD-dependent histone deacetylase activity [ISO]
- NAD-dependent histone deacetylase activity (H4-K16 specific) [ISO, ISS]
- NAD-dependent protein deacetylase activity [IDA, ISO, ISS]
- beta-tubulin binding [ISO]
- chromatin binding [ISO, ISS]
- histone acetyltransferase binding [ISO]
- histone deacetylase activity [ISO, ISS]
- histone deacetylase binding [ISO]
- protein deacetylase activity [ISO, ISS]
- transcription factor binding [ISO]
- tubulin deacetylase activity [IDA, ISO]
- ubiquitin binding [ISO]
- zinc ion binding [ISO]
Gene Ontology Cellular Component
- Schmidt-Lanterman incisure [IDA, ISO, ISS]
- centriole [ISO, ISS]
- centrosome [ISO, ISS]
- chromosome [ISO, ISS]
- cytoplasm [IDA, ISO, ISS]
- cytosol [ISO, ISS]
- glial cell projection [IDA]
- juxtaparanode region of axon [IDA]
- lateral loop [IDA]
- meiotic spindle [ISO, ISS]
- microtubule [ISO]
- midbody [ISO, ISS]
- mitotic spindle [ISO, ISS]
- myelin sheath [IDA, ISO, ISS]
- myelin sheath abaxonal region [IDA]
- nuclear heterochromatin [IDA]
- nucleus [IDA, ISO, ISS]
- paranodal junction [IDA, ISO, ISS]
- paranode region of axon [IDA]
- perikaryon [IDA, ISO, ISS]
- perinuclear region of cytoplasm [ISO, ISS]
- spindle [ISO, ISS]
- terminal loop [IDA]
Download Curated Data for this Protein
262752
10116
Switch View:
- Interactors 2
- Interactions 2
- Network
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3
3
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