Rattus norvegicus
MAP3K5
Ask1, RGD1306565
mitogen-activated protein kinase kinase kinase 5
GO Process (16)
GO Function (9)
GO Component (2)
Gene Ontology Biological Process
- JNK cascade [ISO]
- MAPK cascade [IDA, ISO]
- activation of MAPK activity [ISO]
- activation of MAPKK activity [IDA, ISO]
- activation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- cellular response to hydrogen peroxide [ISO]
- cellular response to reactive nitrogen species [ISO]
- intrinsic apoptotic signaling pathway in response to oxidative stress [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of neuron death [ISO]
- positive regulation of protein phosphorylation [IDA]
- programmed necrotic cell death [ISO]
- protein phosphorylation [ISO]
- regulation of cell death [ISO]
- response to ischemia [IEP]
Gene Ontology Molecular Function- ATP binding [ISO]
- MAP kinase kinase kinase activity [IDA, ISO]
- cysteine-type endopeptidase activator activity involved in apoptotic process [ISO]
- magnesium ion binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- protein kinase activity [ISO]
- protein kinase binding [ISO]
- protein phosphatase binding [ISO]
- ATP binding [ISO]
- MAP kinase kinase kinase activity [IDA, ISO]
- cysteine-type endopeptidase activator activity involved in apoptotic process [ISO]
- magnesium ion binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- protein kinase activity [ISO]
- protein kinase binding [ISO]
- protein phosphatase binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
265112
10116
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- Interactors 5
- Interactions 7
- Network