Rattus norvegicus
RUNX2
Cbfa1, OSF-2
runt-related transcription factor 2
GO Process (32)
GO Function (12)
GO Component (5)
Gene Ontology Biological Process
- BMP signaling pathway [ISO]
- T cell differentiation [ISO]
- cell maturation [ISO]
- cellular response to BMP stimulus [ISO]
- cellular response to fibroblast growth factor stimulus [IEP]
- chondrocyte development [ISO]
- chondrocyte differentiation [ISO]
- embryonic cranial skeleton morphogenesis [ISO]
- embryonic forelimb morphogenesis [ISO]
- endochondral ossification [ISO]
- negative regulation of smoothened signaling pathway [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- odontogenesis of dentin-containing tooth [ISO]
- osteoblast development [ISO]
- osteoblast differentiation [ISO]
- osteoblast fate commitment [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of chondrocyte differentiation [ISO]
- positive regulation of gene expression [ISO]
- positive regulation of ossification [IMP]
- positive regulation of osteoblast differentiation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of fibroblast growth factor receptor signaling pathway [ISO]
- regulation of odontogenesis of dentin-containing tooth [ISO]
- regulation of ossification [ISO]
- regulation of osteoblast differentiation [ISO, TAS]
- skeletal system development [ISO]
- skeletal system morphogenesis [ISO]
- stem cell differentiation [ISO]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function- DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II core promoter sequence-specific DNA binding [ISO]
- bHLH transcription factor binding [ISO]
- chromatin binding [ISO]
- histone deacetylase binding [IPI]
- protein domain specific binding [ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO, TAS]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [ISO]
- DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II core promoter sequence-specific DNA binding [ISO]
- bHLH transcription factor binding [ISO]
- chromatin binding [ISO]
- histone deacetylase binding [IPI]
- protein domain specific binding [ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO, TAS]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
266386
10116
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- Interactors 3
- Interactions 6
- Network