Saccharomyces cerevisiae (S288c)
PDI1
MFP1, TRG1, protein disulfide isomerase PDI1, L000001360, YCL043C
Protein disulfide isomerase; multifunctional protein of ER lumen, essential for formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds; key regulator of Ero1p; forms complex with Mnl1p that has exomannosidase activity, processing unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2, promoting degradation in unfolded protein response; PDI1 has a paralog, EUG1, that arose from the whole genome duplication
GO Process (1)
GO Function (4)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
30941
559292
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- Interactors 400
- Interactions 493
- Network
- PTM Sites 11