Saccharomyces cerevisiae (S288c)

MSH3

mismatch repair protein MSH3, L000001191, YCR092C

Mismatch repair protein; forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability

GO Process (7)

GO Function (7)

GO Component (4)

Gene Ontology Biological Process

DNA recombination [IMP]

maintenance of DNA repeat elements [IBA]

meiotic mismatch repair [IMP]

mismatch repair [IMP]

mitotic recombination [IMP]

reciprocal meiotic recombination [IBA]

removal of nonhomologous ends [IGI, IMP]

Gene Ontology Molecular Function

DNA insertion or deletion binding [IDA]
DNA-dependent ATPase activity [IBA]
Y-form DNA binding [IDA]
damaged DNA binding [IBA]
double-strand/single-strand DNA junction binding [IDA]
heteroduplex DNA loop binding [IDA]
mismatched DNA binding [IDA]

Gene Ontology Cellular Component

MutSbeta complex [IPI]

cytoplasm [IDA]

nuclear chromosome [IBA]

nucleus [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31064

559292

Interactors 117
Interactions 165
Network
PTM Sites 2

Result Summary

MSH3

Gene Ontology Biological Process

Gene Ontology Molecular Function

DNA insertion or deletion binding [IDA]DNA-dependent ATPase activity [IBA]Y-form DNA binding [IDA]damaged DNA binding [IBA]double-strand/single-strand DNA junction binding [IDA]heteroduplex DNA loop binding [IDA]mismatched DNA binding [IDA]

Gene Ontology Cellular Component

DNA insertion or deletion binding [IDA]
DNA-dependent ATPase activity [IBA]
Y-form DNA binding [IDA]
damaged DNA binding [IBA]
double-strand/single-strand DNA junction binding [IDA]
heteroduplex DNA loop binding [IDA]
mismatched DNA binding [IDA]