Saccharomyces cerevisiae (S288c)

UBP6

L000004586, YFR010W
Ubiquitin-specific protease; situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; negatively regulates degradation of ubiquitinated proteins by the proteasome; works in opposition to Hul5p polyubiquitin elongation activity; mutant has aneuploidy tolerance
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31160
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  • Interactors 710
  • Interactions 1,218
  • Network
  • PTM Sites 35