Saccharomyces cerevisiae (S288c)

RPL8B

KRB1, SCL41, ribosomal 60S subunit protein L8B, L8e, rp6, YL5, L8B, L4B, L000000911, L000001705, YLL045C
Ribosomal 60S subunit protein L8B; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; L8 binds to Domain I of 25S and 5.8 S rRNAs; mutation results in decreased amounts of free 60S subunits; homologous to mammalian ribosomal protein L7A, no bacterial homolog; RPL8B has a paralog, RPL8A, that arose from the whole genome duplication
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  • Interactors 485
  • Interactions 623
  • Network
  • PTM Sites 27