Saccharomyces cerevisiae (S288c)


LMA1, thioredoxin TRX1, L000002357, YLR043C
Cytoplasmic thioredoxin isoenzyme; part of thioredoxin system which protects cells against oxidative and reductive stress; forms LMA1 complex with Pbi2p; acts as a cofactor for Tsa1p; required for ER-Golgi transport and vacuole inheritance; with Trx2p, facilitates mitochondrial import of small Tims Tim9p, Tim10p, Tim13p by maintaining them in reduced form; abundance increases iunder DNA replication stress; TRX1 has a paralog, TRX2, that arose from the whole genome duplication
Download Curated Data for this Protein
Switch View:
  • Interactors 79
  • Interactions 110
  • Network
  • PTM Sites 9