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Saccharomyces cerevisiae (S288c)

PDC1

indolepyruvate decarboxylase 1, L000001354, YLR044C

Major of three pyruvate decarboxylase isozymes; key enzyme in alcoholic fermentation; decarboxylates pyruvate to acetaldehyde; involved in amino acid catabolism; subject to glucose-, ethanol-, and autoregulation; activated by phosphorylation in response to glucose levels; N-terminally propionylated in vivo

GO Process (5)

GO Function (2)

GO Component (3)

Gene Ontology Biological Process

L-phenylalanine catabolic process [IGI]

aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [IGI]

glycolytic fermentation to ethanol [IDA]

pyruvate metabolic process [IDA]

tryptophan catabolic process [IGI]

Gene Ontology Molecular Function

branched-chain-2-oxoacid decarboxylase activity [IMP]
pyruvate decarboxylase activity [IDA]

Gene Ontology Cellular Component

cytoplasm [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31319

559292

Interactors 287
Interactions 339
Network
PTM Sites 48