Saccharomyces cerevisiae (S288c)

TIS11

CTH2, L000002895, YLR136C
mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; TIS11 has a paralog, CTH1, that arose from the whole genome duplication
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  • Interactors 62
  • Interactions 76
  • Network
  • PTM Sites 14