Saccharomyces cerevisiae (S288c)

RFX1

CRT1, L000004129, YLR176C

Major transcriptional repressor of DNA-damage-regulated genes; recruits repressors Tup1p and Cyc8p to their promoters; involved in DNA damage and replication checkpoint pathway; similar to a family of mammalian DNA binding RFX1-4 proteins

GO Process (2)

GO Function (2)

GO Component (2)

Gene Ontology Biological Process

negative regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP]

positive regulation of transcription from RNA polymerase II promoter [IMP]

Gene Ontology Molecular Function

RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
sequence-specific DNA binding [IDA]

Gene Ontology Cellular Component

cytoplasm [IDA]

nucleus [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31447

559292

Interactors 180
Interactions 242
Network
PTM Sites 5

Result Summary

RFX1

Gene Ontology Biological Process

Gene Ontology Molecular Function

RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]sequence-specific DNA binding [IDA]

Gene Ontology Cellular Component

RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
sequence-specific DNA binding [IDA]