Saccharomyces cerevisiae (S288c)

HRD3

ubiquitin ligase complex subunit HRD3, L000003040, YLR207W

ER membrane protein that plays a central role in ERAD; forms HRD complex with Hrd1p and ER-associated protein degradation (ERAD) determinants that engages in lumen to cytosol communication and coordination of ERAD events

UPS Project

GO Process (2)

GO Function (1)

GO Component (4)

Gene Ontology Biological Process

ER-associated ubiquitin-dependent protein catabolic process [IDA]

retrograde protein transport, ER to cytosol [IMP]

Gene Ontology Molecular Function

ubiquitin-protein transferase activity [IDA]

Gene Ontology Cellular Component

Hrd1p ubiquitin ligase ERAD-L complex [IDA]

Hrd1p ubiquitin ligase ERAD-M complex [IDA]

endoplasmic reticulum membrane [IPI]

luminal surveillance complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31475

559292

Interactors 125
Interactions 249
Network
PTM Sites 10

Result Summary

HRD3

Gene Ontology Biological Process

Gene Ontology Molecular Function

ubiquitin-protein transferase activity [IDA]

Gene Ontology Cellular Component