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Saccharomyces cerevisiae (S288c)

ECM22

L000004375, YLR228C

Sterol regulatory element binding protein; regulates transcription of sterol biosynthetic genes; contains Zn[2]-Cys[6] binuclear cluster; relocates from intracellular membranes to perinuclear foci on sterol depletion; ECM22 has a paralog, UPC2, that arose from the whole genome duplication

GO Process (2)

GO Function (3)

GO Component (3)

Gene Ontology Biological Process

positive regulation of ergosterol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter [IMP]

positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter [IGI]

Gene Ontology Molecular Function

RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, IMP]
sequence-specific DNA binding [IDA]

Gene Ontology Cellular Component

perinuclear region of cytoplasm [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31498

559292

Interactors 115
Interactions 137
Network
PTM Sites 6