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Saccharomyces cerevisiae (S288c)

EST1

L000000588, YLR233C

TLC1 RNA-associated factor involved in telomere length regulation; recruitment subunit of telomerase; has G-quadruplex promoting activity required for telomere elongation; possible role in activating telomere-bound Est2p-TLC1-RNA; EST1 has a paralog, EBS1, that arose from the whole genome duplication

GO Process (3)

GO Function (3)

GO Component (3)

Gene Ontology Biological Process

G-quadruplex DNA formation [IDA]

telomere maintenance [IMP]

telomere maintenance via telomerase [IDA, IMP]

Gene Ontology Molecular Function

RNA binding [IPI]
single-stranded DNA binding [IDA]
telomeric DNA binding [IDA]

Gene Ontology Cellular Component

nucleolus [IDA]

telomerase holoenzyme complex [IDA, IPI]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31502

559292

Interactors 718
Interactions 880
Network
PTM Sites 2