Saccharomyces cerevisiae (S288c)

IRC20

E3 ubiquitin-protein ligase IRC20, YLR247C
E3 ubiquitin ligase and putative helicase; involved in synthesis-dependent strand annealing-mediated homologous recombination; ensures precise end-joining along with Srs2p in the Yku70p/Yku80p/Lig4p-dependent nonhomologous end joining (NHEJ) pathway; localizes to both the mitochondrion and the nucleus; contains a Snf2/Swi2 family ATPase/helicase and a RING finger domain; interacts with Cdc48p and Smt3p; null mutant displays increased levels of spontaneous Rad52p foci
UBI
PHO
SUMO
GO Process (2)
GO Function (2)
GO Component (2)

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB
Download 111 Published Interactions For This Protein
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  • Interactors (94)
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  • PTM Sites (3)