Saccharomyces cerevisiae (S288c)

HSP60

CPN60, MIF4, MNA2, chaperone ATPase HSP60, L000000819, YLR259C

Tetradecameric mitochondrial chaperonin; required for ATP-dependent folding of precursor polypeptides and complex assembly; prevents aggregation and mediates protein refolding after heat shock; role in mtDNA transmission; phosphorylated

GO Process (6)

GO Function (5)

GO Component (2)

Gene Ontology Biological Process

'de novo' protein folding [IMP]

chaperone-mediated protein complex assembly [IMP]

protein import into mitochondrial intermembrane space [IMP]

protein maturation [IMP]

protein refolding [IDA, IMP]

protein stabilization [IMP]

Gene Ontology Molecular Function

ATPase activity [IDA]
DNA replication origin binding [IDA]
chaperone binding [IPI]
single-stranded DNA binding [IDA]
unfolded protein binding [IMP]

Gene Ontology Cellular Component

mitochondrial nucleoid [IDA]

mitochondrion [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31527

559292

Interactors 406
Interactions 464
Network
PTM Sites 10

Result Summary

HSP60

Gene Ontology Biological Process

Gene Ontology Molecular Function

ATPase activity [IDA]DNA replication origin binding [IDA]chaperone binding [IPI]single-stranded DNA binding [IDA]unfolded protein binding [IMP]

Gene Ontology Cellular Component

ATPase activity [IDA]
DNA replication origin binding [IDA]
chaperone binding [IPI]
single-stranded DNA binding [IDA]
unfolded protein binding [IMP]