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Saccharomyces cerevisiae (S288c)

YSH1

BRR5, L000003344, YLR277C

Putative endoribonuclease; subunit of the mRNA cleavage and polyadenylation specificity complex; required for 3' processing, splicing, and transcriptional termination of mRNAs and snoRNAs; protein abundance increases in response to DNA replication stress; YSH1 has a paralog, SYC1, that arose from the whole genome duplication

GO Process (6)

GO Function (2)

GO Component (2)

Gene Ontology Biological Process

RNA splicing [IMP]

mRNA cleavage [IMP]

mRNA polyadenylation [IMP]

snoRNA 3'-end processing [IMP]

snoRNA splicing [IMP]

termination of RNA polymerase II transcription [IMP]

Gene Ontology Molecular Function

RNA binding [IC]
endoribonuclease activity [IMP, ISS]

Gene Ontology Cellular Component

mRNA cleavage and polyadenylation specificity factor complex [IDA, IPI]

mRNA cleavage factor complex [IPI]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31545

559292

Interactors 42
Interactions 153
Network
PTM Sites 5