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Saccharomyces cerevisiae (S288c)

VPS36

GRD12, VAC3, VPL11, ESCRT-II subunit protein VPS36, L000002958, YLR417W

Component of the ESCRT-II complex; contains the GLUE (GRAM Like Ubiquitin binding in EAP45) domain which is involved in interactions with ESCRT-I and ubiquitin-dependent sorting of proteins into the endosome; plays a role in the formation of mutant huntingtin (Htt) aggregates in yeast

GO Process (4)

GO Function (1)

GO Component (1)

Gene Ontology Biological Process

negative regulation of transcription from RNA polymerase II promoter by glucose [IMP]

protein retention in Golgi apparatus [IMP]

protein targeting to vacuole [IMP, IPI]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [IC]

Gene Ontology Molecular Function

ubiquitin binding [IDA]

Gene Ontology Cellular Component

ESCRT II complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31675

559292

Interactors 171
Interactions 223
Network
PTM Sites 1