Saccharomyces cerevisiae (S288c)

PRP45

FUN20, mRNA splicing protein PRP45, L000000638, YAL032C

Protein required for pre-mRNA splicing; associates with the spliceosome and interacts with splicing factors Prp22p and Prp46p; orthologous to human transcriptional coactivator SKIP and can activate transcription of a reporter gene

GO Process (1)

GO Function (2)

GO Component (4)

Gene Ontology Biological Process

generation of catalytic spliceosome for second transesterification step [IGI, IMP]

Gene Ontology Molecular Function

first spliceosomal transesterification activity [IC]
second spliceosomal transesterification activity [IC]

Gene Ontology Cellular Component

U2-type catalytic step 1 spliceosome [IDA]

U2-type catalytic step 2 spliceosome [IDA]

nucleus [IDA]

post-mRNA release spliceosomal complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31734

559292

Interactors 273
Interactions 380
Network
PTM Sites 1

Result Summary

PRP45

Gene Ontology Biological Process

Gene Ontology Molecular Function

first spliceosomal transesterification activity [IC]second spliceosomal transesterification activity [IC]

Gene Ontology Cellular Component

first spliceosomal transesterification activity [IC]
second spliceosomal transesterification activity [IC]