Saccharomyces cerevisiae (S288c)
GPB2
KRH1, YAL056W
Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; GPB2 has a paralog, GPB1, that arose from the whole genome duplication
GO Process (7)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- ascospore formation [IMP]
- glucose mediated signaling pathway [IGI, IMP]
- invasive growth in response to glucose limitation [IGI, IMP]
- negative regulation of Ras protein signal transduction [IGI]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- pseudohyphal growth [IGI, IMP]
- signal transduction [IPI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
31773
559292
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- Interactors 120
- Interactions 168
- Network
- PTM Sites 8