Saccharomyces cerevisiae (S288c)

MSH5

MutS family protein MSH5, L000002573, YDL154W

Protein of the MutS family; forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans

GO Process (4)

GO Function (3)

GO Component (3)

Gene Ontology Biological Process

chiasma assembly [IBA]

homologous chromosome segregation [IBA]

meiotic mismatch repair [IRD]

reciprocal meiotic recombination [IMP]

Gene Ontology Molecular Function

DNA-dependent ATPase activity [IBA]
damaged DNA binding [IRD]
mismatched DNA binding [IBA]

Gene Ontology Cellular Component

mismatch repair complex [IRD]

nucleus [IDA]

synaptonemal complex [IBA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31909

559292

Interactors 39
Interactions 45
Network

Result Summary

MSH5

Gene Ontology Biological Process

Gene Ontology Molecular Function

DNA-dependent ATPase activity [IBA]damaged DNA binding [IRD]mismatched DNA binding [IBA]

Gene Ontology Cellular Component

DNA-dependent ATPase activity [IBA]
damaged DNA binding [IRD]
mismatched DNA binding [IBA]